745138
(1S,2R)-cis-N-Boc-1,2-cyclopentanediamine
≥97% (TLC)
Synonym(s):
(1R,2S)-2-(Boc-amino)cyclopentylamine, (1S)-cis-N-Boc-1,2-diaminocyclopentane, tert-Butyl ((1S,2R)-2-aminocyclopentyl)carbamate
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About This Item
Empirical Formula (Hill Notation):
C10H20N2O2
CAS Number:
Molecular Weight:
200.28
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:
InChI
1S/C10H20N2O2/c1-10(2,3)14-9(13)12-8-6-4-5-7(8)11/h7-8H,4-6,11H2,1-3H3,(H,12,13)/t7-,8+/m1/s1
SMILES string
N[C@H]1[C@@H](NC(OC(C)(C)C)=O)CCC1
InChI key
PAXDIBGWURAVIH-SFYZADRCSA-N
assay
≥97% (TLC)
form
solid
optical purity
enantiomeric excess: ≥95.0%
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Reinhold Schirmbeck et al.
European journal of immunology, 33(12), 3342-3352 (2003-11-25)
Processing exogenous hepatitis B surface antigen (HBsAg) of the hepatitis B virus (HBV) generates the K(b)-binding S(208-215) epitope 1; processing endogenous HBsAg generates the K(b)-binding S(190-197) epitope 2. Cross-reactive CD8(+) T cell responses were primed to epitope 1 but not
U Sandhu et al.
Nucleic acids research, 39(1), e1-e1 (2010-10-12)
Recombinant mouse strains that harbor tightly controlled transgene expression proved to be indispensible tools to elucidate gene function. Different strategies have been employed to achieve controlled induction of the transgene. However, many models are accompanied by a considerable level of
Z Trobonjaca et al.
Journal of immunology (Baltimore, Md. : 1950), 167(3), 1413-1422 (2001-07-24)
A prominent subset of the hepatic innate immune system is alpha-galactosylceramide (alphaGalCer)-reactive, (CD4(+) and CD4(-)CD8(-)) CD1d-restricted NKT cells. We investigated in C57BL/6 (B6) mice which hepatic cell type stimulates hepatic NKT cell activation. Surface expression of CD1d but not CD40
Zlatko Trobonjaca et al.
Journal of immunology (Baltimore, Md. : 1950), 168(8), 3763-3770 (2002-04-09)
Dendritic cell (DC)-dependent activation of liver NKT cells triggered by a single i.v. injection of a low dose (10-100 ng/mouse) of alpha-galactosyl ceramide (alphaGalCer) into mice induces liver injury. This response is particularly evident in HBs-tg B6 mice that express
Petra Riedl et al.
Journal of immunology (Baltimore, Md. : 1950), 183(1), 370-380 (2009-06-23)
Immunodominance limits the TCR diversity of specific antiviral CD8 T cell responses elicited by vaccination or infection. To prime multispecific T cell responses, we constructed DNA vaccines that coexpress chimeric, multidomain Ags (with CD8 T cell-defined epitopes of the hepatitis
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