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Merck
CN

745138

Sigma-Aldrich

(1S,2R)-cis-N-Boc-1,2-cyclopentanediamine

≥97% (TLC)

Synonym(s):

(1R,2S)-2-(Boc-amino)cyclopentylamine, (1S)-cis-N-Boc-1,2-diaminocyclopentane, tert-Butyl ((1S,2R)-2-aminocyclopentyl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C10H20N2O2
CAS Number:
445479-01-6
Molecular Weight:
200.28
MDL number:
MFCD18831394
UNSPSC Code:
12352108
PubChem Substance ID:
329764966
NACRES:
NA.22

Key Documents

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Assay

≥97% (TLC)

form

solid

optical purity

enantiomeric excess: ≥95.0%

SMILES string

N[C@H]1[C@@H](NC(OC(C)(C)C)=O)CCC1

InChI

1S/C10H20N2O2/c1-10(2,3)14-9(13)12-8-6-4-5-7(8)11/h7-8H,4-6,11H2,1-3H3,(H,12,13)/t7-,8+/m1/s1

InChI key

PAXDIBGWURAVIH-SFYZADRCSA-N

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H315,H318

Precautionary Statements

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBV3265
BCBL0611V
BCBL0611

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Reinhold Schirmbeck et al.
European journal of immunology, 33(12), 3342-3352 (2003-11-25)
Processing exogenous hepatitis B surface antigen (HBsAg) of the hepatitis B virus (HBV) generates the K(b)-binding S(208-215) epitope 1; processing endogenous HBsAg generates the K(b)-binding S(190-197) epitope 2. Cross-reactive CD8(+) T cell responses were primed to epitope 1 but not
U Sandhu et al.
Nucleic acids research, 39(1), e1-e1 (2010-10-12)
Recombinant mouse strains that harbor tightly controlled transgene expression proved to be indispensible tools to elucidate gene function. Different strategies have been employed to achieve controlled induction of the transgene. However, many models are accompanied by a considerable level of
Zlatko Trobonjaca et al.
Journal of immunology (Baltimore, Md. : 1950), 168(8), 3763-3770 (2002-04-09)
Dendritic cell (DC)-dependent activation of liver NKT cells triggered by a single i.v. injection of a low dose (10-100 ng/mouse) of alpha-galactosyl ceramide (alphaGalCer) into mice induces liver injury. This response is particularly evident in HBs-tg B6 mice that express
Z Trobonjaca et al.
Journal of immunology (Baltimore, Md. : 1950), 167(3), 1413-1422 (2001-07-24)
A prominent subset of the hepatic innate immune system is alpha-galactosylceramide (alphaGalCer)-reactive, (CD4(+) and CD4(-)CD8(-)) CD1d-restricted NKT cells. We investigated in C57BL/6 (B6) mice which hepatic cell type stimulates hepatic NKT cell activation. Surface expression of CD1d but not CD40
Petra Riedl et al.
Journal of immunology (Baltimore, Md. : 1950), 183(1), 370-380 (2009-06-23)
Immunodominance limits the TCR diversity of specific antiviral CD8 T cell responses elicited by vaccination or infection. To prime multispecific T cell responses, we constructed DNA vaccines that coexpress chimeric, multidomain Ags (with CD8 T cell-defined epitopes of the hepatitis

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