745774
8-Amino-1-octanethiol hydrochloride
95%
Synonym(s):
8-Mercaptooctylamine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C8H19NS · HCl
CAS Number:
Molecular Weight:
197.77
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:
Product Name
8-Amino-1-octanethiol hydrochloride, 95%
InChI
1S/C8H19NS.ClH/c9-7-5-3-1-2-4-6-8-10;/h10H,1-9H2;1H
SMILES string
SCCCCCCCCN.Cl
InChI key
CCWZBRKMJBSNQS-UHFFFAOYSA-N
assay
95%
form
solid
mp
158-163 °C
storage temp.
2-8°C
Quality Level
Related Categories
Application
8-AOT can be used in the surface functionalization of gold electrodes for the trace analysis of oligonucleotide using poly nucleic acid (PNA) based ion-channel sensors. It can be used in the fabrication of peptide microarray for surface plasmon resonance based screening of protein kinase activity.
Self Assembly Molecules (SAMs); the amino group is usually modified using amine-reactive materials; such as proteins or biomaterials; to functionalize the gold surface. It is used for biosenors with large amounts of immobilized protein and suppression of nonspecific adsorption
General description
8-Amino-1-octanethiol hydrochloride (8-AOT) is an amine based alkanethiol that can be used as a self-assembled monolayer (SAM) on a variety of surfaces. It facilitates the immobilization of surface atoms and controls the physiochemical properties of the substrate.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Tillmann Utesch et al.
Langmuir : the ACS journal of surfaces and colloids, 28(13), 5761-5769 (2012-03-06)
Sulfite oxidase (SO) is an enzyme catalyzing the terminal step of the metabolism of sulfur-containing amino acids that is essential for almost all living organisms. The catalytic activity of SO in vertebrates strongly depends on the efficiency of the intramolecular
Trace analysis of an oligonucleotide with a specific sequence using PNA-based ion-channel sensors
Aoki H and Umezawa Y
Analyst, 128(6), 681-685 (2003)
Tuning the surface potential of gold substrates arbitrarily with self-assembled monolayers with mixed functional groups
Lin W, et al.
Physical Chemistry Chemical Physics, 11(29), 6199-6204 (2009)
Photooxidation of amine-terminated self-assembled monolayers on gold
Lee S, et al.
The Journal of Physical Chemistry C, 114(23), 10512-10519 (2010)
Evaluation of protein kinase activities of cell lysates using peptide microarrays based on surface plasmon resonance imaging
Mori T, et al.
Analytical Biochemistry, 375(2), 223-231 (2008)
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