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Merck
CN

746134

Chitosan

Mv 40,000-60,000

Synonym(s):

KiOmedine-CsU®A, Deacetylated chitin, Poly(D-glucosamine)

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About This Item

CAS Number:
UNSPSC Code:
12352200
MDL number:
Technical Service
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mol wt

Mv 40,000-60,000

composition

Bacterial endotoxins, ≤10 EU/g , Beta-glucan, ≤5 % (w/w) , Chitosan content, ≥93 % (w/w) , Degree of acetylation, ≤40 mol % , Proteins, ≤1 % (w/w)

viscosity

5-200 mPa.s, 1 % in 1% acetic acid

solubility

acetic acid: 1% (solution)

storage temp.

2-8°C

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI key

FLASNYPZGWUPSU-SICDJOISSA-N

General description

KiOmedine®-CsU is an ultra-pure chitosan of non-animal origin, produced from white mushrooms (Agaricus bisporus), in accordance with cGMP.
The crystalline structure is in the α-form. The linkage between glucosamine units is β-(1,4).

Application

These chitosans are high-value; medical grade polymers manufactured under cGMP conditions; commonly used in surface modification; tissue engineering; and drug delivery.
Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.
Biocompatible, antibacterial and environmentally friendly polyelectrolyte.

Legal Information

Product of KitoZyme
Kalignost is a registered trademark of Heyl Chemisch-Pharmazeutische Fabrik GmbH & Co. KG
KiOmedine is a registered trademark of KitoZyme, S.A.


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Storage Class

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Abdelkrim El Kadib et al.
Journal of nanoscience and nanotechnology, 14(1), 308-331 (2014-04-16)
Polysaccharides are a new class of pervasive biopolymers that display many advantages including wide availability, sustainability, inherent inclusion of chemical functionality, biocompatibility and biodegradability. Current efforts are focused on the catalytic transformation of these macromolecules into fuels and platform chemicals.
Liming Hu et al.
Nanoscale, 5(8), 3103-3111 (2013-03-22)
Within the past few years, chitosan-based drug delivery vehicles have become some of the most attractive to be studied. In contrast to all other polysaccharides, chitosan has demonstrated its unique characteristics for drug delivery platforms, including its active primary amino
Alberto Busilacchi et al.
Carbohydrate polymers, 98(1), 665-676 (2013-08-31)
The idea of using chitosan as a functional delivery aid to support simultaneously PRP, stem cells and growth factors (GF) is associated with the intention to use morphogenic biomaterials to modulate the natural healing sequence in bone and other tissues.