760862
Poly(ethylene glycol), 8 hydroxyl dendron, generation 2
average Mn 6,700
Synonym(s):
Bis-MPA poly(ethylene glycol), Bis[2,2-bis(hydroxymethyl)propanoic acid] PEG, Dendron functionalized PEG, generation 2, PFD-G2-PEG6k-OH
mol wt
PEG average Mn 6,000 (n~130; esterified with 8 hydroxyl groups)
average Mn 6,700
feature
generation 2
mp
48-53 °C
functional group
hydroxyl
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General description
Dendrimers are symmetrically branched polymer structures, monodispersed macromolecules. They possess uniform size, water solubiltity, and modifiable surface functionality. Cross linking it with polyethylene glycol results in very high water content.
Application
1. Dendritic nanodevices for therapeutic applications.
2. Surface modified for targeting, imaging and drug delivery
3. Antibody-dendrimer conjugate
4. Anti viral drugs
5. Tissue repair scaffolds
2. Surface modified for targeting, imaging and drug delivery
3. Antibody-dendrimer conjugate
4. Anti viral drugs
5. Tissue repair scaffolds
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Anil K Patri et al.
Current opinion in chemical biology, 6(4), 466-471 (2002-07-23)
Dendrimers are synthetic, highly branched, mono-disperse macromolecules of nanometer dimensions. Started in the mid-1980s, the research investigations into the synthetic methodology, physical and chemical properties of these macromolecules are increasing exponentially with growing interest in this field. Potential applications for
Degradable Poly(ethylene glycol) Hydrogels
for 2D and 3D Cell Culture
for 2D and 3D Cell Culture
Kasko A
Material Matters, 6(3), 67-75 null
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