Skip to Content
Merck
CN

Key Documents

View All Documentation

762334

Diethyl methylphosphonite

97%, liquid

Synonym(s):

Diethoxymethylphosphine

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C5H13O2P
CAS Number:
15715-41-0
Molecular Weight:
136.13
NACRES:
NA.22
PubChem Substance ID:
329766965
UNSPSC Code:
12352108
EC Number:
239-805-9
MDL number:
MFCD00009089
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Diethyl methylphosphonite, 97%

Quality Level

100

assay

97%

form

liquid

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: ligand

refractive index

n20/D 1.419

density

0.907 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

CCOP(C)OCC

InChI

1S/C5H13O2P/c1-4-6-8(3)7-5-2/h4-5H2,1-3H3

InChI key

NSSMTQDEWVTEKN-UHFFFAOYSA-N

Application

Diethyl methylphosphonite can be used as a mild reducing reagent in the oxalimide cyclization of oxalylazetidinonyl thiocarbonates and thioesters. It can also be used in the synthesis of β-carboxamido-phosphon(in)ic acids as potential inhibitors of human mast cell chymase.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

hcodes

H226,H302

Hazard Classifications

Acute Tox. 4 Oral - Flam. Liq. 3

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

84.9 °F

flash_point_c

29.4 °C

Regulatory Information

监管及禁止进口产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCD5671
MKBW1898V
MKBT8338V
MKBQ7060V
MKBN2457V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Alkylphosphonous acid diesters, novel reagents for the oxalimide cyclization to penems.
Budt K H, et al.
Tetrahedron Letters, 33(37), 5331-5334 (1992)
Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase.
Greco M N, et al.
Journal of Medicinal Chemistry, 50(8), 1727-1730 (2007)

Global Trade Item Number

SKUGTIN
762334-1G04061826736111
762334-10G04061833340196
762334-5G04061833340202