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Merck
CN

763772

Sigma-Aldrich

Perchloric acid, silica supported

extent of labeling: 0.35 mmol/g

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About This Item

EC Number:
UNSPSC Code:
12352301
NACRES:
NA.22
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form

powder

extent of labeling

0.35 mmol/g

mp

>400 °C

Application

Perchloric acid, silica-supported (HClO4-SiO2) can be used as a catalyst for:
  • The preparation of amidoalkyl naphthols by the condensation reaction of 2-naphthol, aromatic aldehydes, and acetonitrile.
  • The Friedlander quinoline synthesis by the condensation reaction of 2-aminoaryl ketones and carbonyl compounds.
  • The synthesis of aryl or alkyl-dibenzo xanthenes by the condensation reaction between aldehyde and 2-naphthol.
  • The protection of various hydroxyl functional groups by converting into their corresponding trimethylsilyl ethers using hexamethyldisilazane (HMDS).

Storage Class Code

13 - Non Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

易制爆化学品
危险化学品
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Silica supported perchloric acid (HClO4-SiO2): A highly efficient and reusable catalyst for the protection of hydroxyl groups using HMDS under mild and ambient conditions
Shaterian HR, et al.
J. Mol. Catal. A: Chem., 272(1-2), 142-151 (2007)
Silica supported Perchloric acid (HClO4-SiO2): A mild, reusable and highly efficient heterogeneous catalyst for the synthesis of 14-aryl or alkyl-14-H-dibenzo [a, j] xanthenes
Bigdeli MA, et al.
J. Mol. Catal. A: Chem., 275(1-2), 25-29 (2007)
Silica supported perchloric acid (HClO4-SiO2): an efficient and recyclable heterogeneous catalyst for the one-pot synthesis of amidoalkyl naphthols
Shaterian HR, et al.
Tetrahedron, 64(7), 1263-1269 (2008)
Silica supported perchloric acid: A mild and highly efficient heterogeneous catalyst for the synthesis of poly-substituted quinolines via Friedlander hetero-annulation
Narasimhulu M, et al.
J. Mol. Catal. A: Chem., 266(1-2), 114-117 (2007)

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