764213
Biotin-PEG4-alkyne
for copper catalyzed click labeling
Synonym(s):
Polyethylene glycol, Acetylene-PEG4-biotin conjugate
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About This Item
Empirical Formula (Hill Notation):
C21H35N3O6S
CAS Number:
Molecular Weight:
457.58
MDL number:
UNSPSC Code:
12161502
PubChem Substance ID:
NACRES:
NA.22
Quality Level
assay
95%
form
solid
reaction suitability
reaction type: click chemistry
mp
55-64 °C
storage temp.
−20°C
SMILES string
O=C(NCCOCCOCCOCCOCC#C)CCCC[C@@H](SC1)[C@@]2([H])[C@]1([H])NC(N2)=O
InChI
1S/C21H35N3O6S/c1-2-8-27-10-12-29-14-15-30-13-11-28-9-7-22-19(25)6-4-3-5-18-20-17(16-31-18)23-21(26)24-20/h1,17-18,20H,3-16H2,(H,22,25)(H2,23,24,26)/t17-,18-,20-/m1/s1
InChI key
SKMJWNZZFUDLKQ-QWFCFKBJSA-N
Application
Biotin-PEG4-alkyne may be used for the modification of 4-azidophenylalanine (AzPhe) silk fibroin via bioorthogonal azide–alkyne cycloaddition reaction for developing photopatternable protein material.
Biotinylation reagent for labeling azide containing molecules or biomolecules using copper-catalyzed 1,3 dipolar cycloaddition click chemistry. The alkyne group reacts with azides to form a stable triazole linkage, facilitating the introduction of biotin into your azide modified system of interest.
Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)
Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)
Other Notes
Chemoproteomic Profiling of Gut Microbiota-Associated Bile Salt Hydrolase Activity
Fluorescent Heterotelechelic Single-Chain Polymer Nanoparticles: Synthesis, Spectroscopy, and Cellular Imaging
Arginine-Selective Chemical Labeling Approach for Identification and Enrichment of Reactive Arginine Residues in Proteins
Selective Imaging of Gram-Negative and Gram-Positive Microbiotas in the Mouse Gut
Metabolic Oligosaccharide Engineering with Alkyne Sialic Acids Confers Neuraminidase Resistance and Inhibits Influenza Reproduction
A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level
Fluorescent Heterotelechelic Single-Chain Polymer Nanoparticles: Synthesis, Spectroscopy, and Cellular Imaging
Arginine-Selective Chemical Labeling Approach for Identification and Enrichment of Reactive Arginine Residues in Proteins
Selective Imaging of Gram-Negative and Gram-Positive Microbiotas in the Mouse Gut
Metabolic Oligosaccharide Engineering with Alkyne Sialic Acids Confers Neuraminidase Resistance and Inhibits Influenza Reproduction
A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Ryan T Cassell et al.
Chembiochem : a European journal of chemical biology, 16(7), 1060-1067 (2015-04-01)
The brevetoxins are neurotoxins that are produced by the "Florida red tide" dinoflagellate Karenia brevis. They bind to and activate the voltage-gated sodium channels in higher organisms, specifically the Nav 1.4 and Nav 1.5 channel subtypes. However, the native physiological
Javier Mazuela et al.
Organic letters, 19(20), 5541-5544 (2017-10-06)
The organocatalytic asymmetric transfer hydrogenation of N-alkyl aryl imino esters for the direct synthesis of N-alkylated arylglycinate esters is reported. High yields and enantiomeric ratios were obtained, and tolerance to a diverse set of functional groups facilitated the preparation of
Azide-incorporated clickable silk fibroin materials with the ability to photopattern.
Teramoto H, et al.
ACS biomaterials science & engineering, 2(2), 251-258 (2016)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 764213-10MG | 04061833230954 |
| 764213-5MG | 04061833230961 |