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Merck
CN

766208

Diphenylammonium Triflate

greener alternative

97%

Synonym(s):

DPAT

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About This Item

Empirical Formula (Hill Notation):
C13H12F3NO3S
CAS Number:
Molecular Weight:
319.30
UNSPSC Code:
12352300
PubChem Substance ID:
NACRES:
NA.22
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Assay

97%

form

solid

reaction suitability

reagent type: ligand

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

178-183 °C

greener alternative category

storage temp.

2-8°C

SMILES string

[O-]S(=O)(=O)C(F)(F)F.[NH2+](c1ccccc1)c2ccccc2

InChI

1S/C12H11N.CHF3O3S/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12;2-1(3,4)8(5,6)7/h1-10,13H;(H,5,6,7)

InChI key

MGEGQAUINMTPGX-UHFFFAOYSA-N

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Application

Efficient catalyst for esterification of carboxylic acids and for transesterification of carboxylic
esters with alcohols
Efficient catalyst for greener synthesis of esters by condensation of carboxylic acids with alcohols or transfesterification.
Diphenylammonium triflate (DPAT): efficient catalyst for esterification of carboxylic acids and for transesterification of carboxylic esters with nearly equimolar amounts of alcohols

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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James B Lucot
Autonomic neuroscience : basic & clinical, 202, 97-101 (2016-09-13)
Doses of naloxone far below those which elicit emesis increase the sensitivity to motion sickness. In order to evaluate the possible interaction with broad spectrum antiemetics, low doses of naloxone were tested alone and in combination with 8-hydroxy-2-(di-n-propylamine)tetralin (DPAT), fentanyl
T M Eriksson et al.
Molecular psychiatry, 17(2), 173-184 (2011-01-19)
Cognitive dysfunctions are common in major depressive disorder, but have been difficult to recapitulate in animal models. This study shows that Flinders sensitive line (FSL) rats, a genetic rat model of depression, display a pronounced impairment of emotional memory function
Anna U Odland et al.
ACS chemical neuroscience, 10(7), 3094-3100 (2019-06-28)
Rodents exhibit natural exploratory behaviors, which can be measured by the spontaneous alternation behavior (SAB) test. Perseverance in this test induced by the 5-hydroxytryptamine 1A receptor (5-HT1AR) agonist, 8-hydroxy-2-dipropylaminotetralin (8-OH-DPAT), resembles compulsive behaviors observed in humans and manifests as reduced
José-Ángel García-Pedraza et al.
Clinical and experimental pharmacology & physiology, 44(12), 1224-1231 (2017-08-05)
5-hydroxytryptamine (5-HT) modulates noradrenergic activity in different cardiovascular territories, but its effect on the mesenteric vasopressor outflow has not yet been clarified. This study investigated the in vivo serotonergic influence, characterizing 5-HT receptors implicated, in sympathetic innervation of mesenteric vasculature.
Pascal Amireault et al.
PloS one, 8(12), e83010-e83010 (2013-12-21)
Serotonin (5-HT) is a monoamine originally purified from blood as a vasoactive agent. In nonneuronal tissues, its presence is linked with the expression of tryptophan hydroxylase 1 (TPH1) that catalyzes the rate-limiting step of its synthesis. Targeted disruption in mice

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