767751
2-{2-[2-(2-Mercaptoethoxy)ethoxy]ethoxy}ethanol
97%
Synonym(s):
MEEE, 1-Mercapto-11-hydroxy-3,6,9-trioxaundecane
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About This Item
Empirical Formula (Hill Notation):
C8H18O4S
Molecular Weight:
210.29
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
97%
Form:
liquid
InChI
1S/C8H18O4S/c9-1-2-10-3-4-11-5-6-12-7-8-13/h9,13H,1-8H2
SMILES string
OCCOCCOCCOCCS
InChI key
GKKYNULPAQDGHI-UHFFFAOYSA-N
assay
97%
form
liquid
reaction suitability
reagent type: cross-linking reagent
refractive index
n20/D 1.481
density
1.098 g/mL at 25 °C
Quality Level
Application
2-{2-[2-(2-Mercaptoethoxy)ethoxy]ethoxy}ethanol may be used in the synthesis of 2-(2-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)ethoxy)ethoxy)ethanol, an nitrobenzoxadiazole (NBD) analog of the anticancer agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX). This analog is a potent glutathione S-transferase (GST) and a potential therapeutic antimelanoma agent with enhanced water solubility and antitumor efficacy when compared to NBDHEX in a study.
- Oligo-ehtylene glycol of peptides and small molecules (PEGylation)
- PEG-disulfide formation
- ultra-thin protein-resistant monolayers
- Densely packed monolayer and a flexible-hydrophilic oligo ethylene glycol arm for avoiding non-specific adsorption
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Skin Corr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
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