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Merck
CN

775983

Poly(L-lactide), acrylate terminated

average Mn 5,500, PDI ≤1.2

Synonym(s):

PLA, PLLA acrylate, acrylate-PLA-OH

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About This Item

Linear Formula:
(C3H4O2)nC5H8O3
NACRES:
NA.23
UNSPSC Code:
12162002
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form

solid

mol wt

average Mn 5,500

transition temp

Tm 152-158 °C (158degC, peak experimental), Tg 42 °C

PDI

≤1.2

storage temp.

2-8°C

Application

This poly(L-lactide) is a well-defined, biodegradable polymer which is functionalized with an alcohol on one end and an acrylate on the other. Acrylates are commonly used in polymerizations or in ligatation to thiols with thiol-ene click chemistry. Polylactide is commonly used in several applications including drug delivery, compatibilizer, emulsifier, thermoplastic elastomer or impact-resistant plastic.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Articles

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

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Synthesis of Polymer Network Scaffolds from L-Lactide and Poly(ethylene glycol) and Their Interaction with Cells
Dong Keun Han;
Macromolecules, 30(20) (1997)
Nadege Handke;
Journal of Polymer Science Part A: Polymer Chemistry, 49, 1341-1350 (2011)



Global Trade Item Number

SKUGTIN
775983-1G04061826139875