779717
19-Hydroxy-4-androstene-3,17-dione
≥90% (HPLC)
Synonym(s):
4-Androsten-19-ol-3,17-dione, 4-Androstene-3,17-dione-19-ol
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About This Item
Empirical Formula (Hill Notation):
C19H26O3
CAS Number:
Molecular Weight:
302.41
EC Number:
208-116-5
UNSPSC Code:
12352103
PubChem Substance ID:
Beilstein/REAXYS Number:
2567249
MDL number:
Assay:
≥90% (HPLC)
Form:
crystals
InChI
1S/C19H26O3/c1-18-8-7-16-14(15(18)4-5-17(18)22)3-2-12-10-13(21)6-9-19(12,16)11-20/h10,14-16,20H,2-9,11H2,1H3/t14-,15-,16-,18-,19+/m0/s1
InChI key
XGUHPTGEXRHMQQ-BGJMDTOESA-N
SMILES string
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34CO)[C@@H]1CCC2=O
assay
≥90% (HPLC)
form
crystals
optical activity
[α]/D +190±5°, c = 1 in chloroform
storage temp.
−20°C
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Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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J P Weniger et al.
Reproduction, nutrition, development, 30(2), 253-257 (1990-01-01)
Aromatase activity in the foetal rat testis was demonstrated by the conversion of [3H] testosterone into oestradiol. However, the conversion rate was low, around 0.06%, probably because the radioactive precursor was heavily diluted by the large amounts of endogenous testosterone
[Hypertensinogenic steroid].
M Soma et al.
Nihon rinsho. Japanese journal of clinical medicine, 47(9), 2104-2108 (1989-09-01)
H Sekihara et al.
The Journal of endocrinology, 138(1), 31-40 (1993-07-01)
We have reported that 19-hydroxyandrostenedione (19-OH-A-dione) amplifies the sodium-retaining action of aldosterone. To evaluate whether it also amplifies the hypertensive action of small doses of aldosterone, mononephrectomized rats were given 0.5 mg aldosterone, 10 mg 19-OH-A-dione or a combination of
C K Sites et al.
Journal of assisted reproduction and genetics, 13(6), 505-510 (1996-07-01)
Our objective was to develop a sensitive in vitro bioassay for follicle-stimulating hormone (FSH) that does not require the housing of animals in a research facility. Porcine granulosa cells from 1- to 3-mm follicles were cultured on laminin for 48
M E Hähnel et al.
The Australian & New Zealand journal of obstetrics & gynaecology, 29(3 Pt 1), 238-241 (1989-08-01)
Because of the association of preeclampsia with hydatidiform mole, and since levels of 19-hydroxyandrostenedione (19-OH-A) and androstenedione (A) are raised in hypertensive diseases of pregnancy, we compared plasma 19-OH-A and A in hydatidiform mole patients with control early pregnant women.
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