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Merck
CN

793728

1,3,5,7-Tetramethyl-8-phenyl-4,4-difluoroboradiazaindacene

97%

Synonym(s):

BODIPY dye, Boron dipyrromethene fluorophore, Difluoro{2-[(3,5-dimethyl-2H-pyrrol-2-ylidene-N)phenylmethyl]-3,5-dimethyl-1H-pyrrolato-N}boron

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About This Item

Empirical Formula (Hill Notation):
C19H19BF2N2
CAS Number:
194235-40-0
Molecular Weight:
324.18
MDL number:
MFCD28137455
UNSPSC Code:
12352103
PubChem Substance ID:
329768412
NACRES:
NA.23

Key Documents

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Quality Level

100

Assay

97%

form

powder

mp

174-179 °C

fluorescence

λex 326 nm; λem 515 nm

SMILES string

FB(F)N1C(/C(C2=CC=CC=C2)=C3N=C(C)C=C\3C)=C(C)C=C1C

InChI

1S/C19H19BF2N2/c1-12-10-14(3)23-18(12)17(16-8-6-5-7-9-16)19-13(2)11-15(4)24(19)20(21)22/h5-11H,1-4H3/b18-17-

InChI key

CMLQGCANJGWRFY-ZCXUNETKSA-N

Related Categories

General description

1,3,5,7-Tetramethyl-8-phenyl-4,4-difluoroboradiazaindacene (BODIPY) is a difluoroboradiaza-s-indacene derivative that has high absorption coefficient and quantum yield with photonic properties. It is used as an acceptor molecule that facilitates the formation of fluorescent probes.

Application

BODIPY can be used as an electron donor for thiol-based probes for fluorescent imaging of cellular thiols. It may also be used as a modified dye in the fabrication of organic light emitting diodes (OLEDs).
BODIPY laser dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides, and dextrans, and to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands, and polystyrene microspheres.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCN0669
MKCG1273
MKCC7325
MKBX4075V
MKBS0274V

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Electrogenerated Chemiluminescence and Proton-Dependent Switching of Fluorescence: Functionalized Difluoroboradiaza-s-indacenes
Kollmannsberger M, et al.
Angewandte Chemie (International ed. in English), 36(12), 1333-1335 (1997)
A tetraphenylethene-decorated BODIPY monomer/dimer with intense fluorescence in various matrices
Li Z, et al.
New. J. Chem., 37(11), 3755-3761 (2013)
Styryl-BODIPY based red-emitting fluorescent OFF-ON molecular probe for specific detection of cysteine
Shao J, et al.
Biosensors And Bioelectronics, 26(6), 3012-3017 (2011)
Ultrafast charge transfer in amino-substituted boron dipyrromethene dyes and its inhibition by cation complexation: a new design concept for highly sensitive fluorescent probes
Kollmannsberger M, et al.
The Journal of Physical Chemistry A, 102(50), 10211-10220 (1998)
Xiaotong Su et al.
Animals : an open access journal from MDPI, 9(12) (2019-12-15)
Neudesin neurotrophic factor (NENF) is a secreted protein that is essential in multiple biological processes, including neural functions, adipogenesis, and tumorigenesis. In our previous study, NENF was significantly inhibited in the bovine adipocytes-myoblasts co-culture system. However, studies on NENF regulation
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