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Merck
CN

808148

TcBoc-Leu-OH

≥95%, powder

Synonym(s):

N-(2,2,2-Trichloro-tert-butoxy)carbonyl-leucine

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About This Item

Empirical Formula (Hill Notation):
C11H18Cl3NO4
CAS Number:
Molecular Weight:
334.62
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22
MDL number:
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Product Name

TcBoc-Leu-OH, ≥95%

InChI

1S/C11H18Cl3NO4/c1-6(2)5-7(8(16)17)15-9(18)19-10(3,4)11(12,13)14/h6-7H,5H2,1-4H3,(H,15,18)(H,16,17)/t7-/m0/s1

InChI key

LMPYDSRXIGDZAB-ZETCQYMHSA-N

assay

≥95%

form

powder

reaction suitability

reaction type: C-H Activation
reagent type: ligand
reaction type: Peptide Synthesis

mp

108-113 °C

application(s)

peptide synthesis

functional group

amine
carboxylic acid

Application

Amino acid as a chiral ligand for enantioselective activation of C-H bond.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

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Pd(II)-catalyzed enantioselective activation of C(sp2)-H and C(sp3)-H bonds using monoprotected amino acids as chiral ligands.
Bing-Feng Shi et al.
Angewandte Chemie (International ed. in English), 47(26), 4882-4886 (2008-05-20)

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