808482
Poly(D,L-lactide-co-glycolide)
lactide:glycolide 50:50, acid and hydroxy terminated, Mn 25000
Synonym(s):
HO-PLGA-COOH, PLGA, heterobifunctional PLGA
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About This Item
Linear Formula:
HO(C3H4O2)x(C2H2O2)yH
UNSPSC Code:
12162002
form
crystals
mol wt
Mn 25000
storage temp.
2-8°C
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Application
Heterobifunctional degradable PLGA for conjugation, grafting and functionalization for drug delivery applications.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Saurabh Srivastava et al.
Journal of cancer research and therapeutics, 15(3), 480-490 (2019-06-07)
The aim of the study to develop surface modified targeted moiety α-tocopherol (α-t) encapsulated with 5-fluorouracil (5-FU)-poly-D, L-lactic-co-glycolic acid nanoparticles (PLGA NPs) toward the anticancer activity against oral squamous cell carcinoma (OSCC). 5-FU was conjugated with the polymer, PLGA by
Grafting of telechelic poly(lactic-co-glycolic acid) onto O2 plasma-treated polypropylene flakes.
Ren J, et al.
Journal of Applied Polymer Science, 121, 210-216 (2011)
Kun Wei et al.
International journal of pharmaceutics, 464(1-2), 225-233 (2014-01-28)
Di-block polymer of poly (lactic-co-glycolic acid)-poly (ethylene glycol) (PLGA-PEG) end-capped with capecitabine (CAP) at the hydrophobic domain and folate (FA) at hydrophilic domain were synthesized respectively. The products were extensively studied by nuclear magnetic resonance ((1)H NMR) and gel permeation
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