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Merck
CN

809047

(+)-Men-Leu-OH

Synonym(s):

N-(+)-Menthylcarbonyl-Leucine

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About This Item

Empirical Formula (Hill Notation):
C17H31NO4
CAS Number:
Molecular Weight:
313.43
PubChem Substance ID:
UNSPSC Code:
12352116
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InChI

1S/C17H31NO4/c1-10(2)8-14(16(19)20)18-17(21)22-15-9-12(5)6-7-13(15)11(3)4/h10-15H,6-9H2,1-5H3,(H,18,21)(H,19,20)/t12-,13+,14-,15-/m0/s1

InChI key

JDNKQMWGCKCHBF-XGUBFFRZSA-N

SMILES string

O=C(O)[C@H](CC(C)C)NC(O[C@@H]1[C@@H](C(C)C)CC[C@H](C)C1)=O

form

powder

reaction suitability

reaction type: C-H Activation
reagent type: ligand
reaction type: Peptide Synthesis

application(s)

peptide synthesis

functional group

amine
carboxylic acid

Application

Menthol-derived mono-protected L-amino acid (MPAA) ligand is for β-arylation C-H functionalization, developed by the Jin Quan Yu group.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Related Content

Yu program focuses on efficient C–H bond activation for drug synthesis, using simple starting materials.

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