84607
SCAL-Linker
technical, ≥90% (HPLC)
Synonym(s):
4,4′-Bis(methylsulfinyl)-2-(4-carboxybutoxy)-N-Fmoc-benzhydrylamine, Safety catch amide linker
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About This Item
Empirical Formula (Hill Notation):
C35H35NO7S2
CAS Number:
Molecular Weight:
645.78
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
SMILES string
CS(=O)c1ccc(cc1)C(NC(=O)OCC2c3ccccc3-c4ccccc24)c5ccc(cc5OCCCCC(O)=O)S(C)=O
grade
technical
assay
≥90% (HPLC)
reaction suitability
reagent type: cross-linking reagent
storage temp.
2-8°C
Other Notes
Safety-catch anchoring linker for solid-phase peptide synthesis
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A Brik et al.
The Journal of organic chemistry, 65(12), 3829-3835 (2000-06-24)
The native chemical ligation reaction has been used extensively for the synthesis of the large polypeptides that correspond to folded proteins and domains. The efficiency of the synthesis of the target protein is highly dependent on the number of peptide
M. Patek et al.
Proc. 13th Am. Peptide Symp., 146-146 (1993)
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