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Merck
CN

84607

Sigma-Aldrich

SCAL-Linker

technical, ≥90% (HPLC)

Synonym(s):

4,4′-Bis(methylsulfinyl)-2-(4-carboxybutoxy)-N-Fmoc-benzhydrylamine, Safety catch amide linker

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About This Item

Empirical Formula (Hill Notation):
C35H35NO7S2
CAS Number:
Molecular Weight:
645.78
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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grade

technical

Assay

≥90% (HPLC)

reaction suitability

reagent type: cross-linking reagent

storage temp.

2-8°C

SMILES string

CS(=O)c1ccc(cc1)C(NC(=O)OCC2c3ccccc3-c4ccccc24)c5ccc(cc5OCCCCC(O)=O)S(C)=O

Other Notes

Safety-catch anchoring linker for solid-phase peptide synthesis

Regulatory Information

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A Brik et al.
The Journal of organic chemistry, 65(12), 3829-3835 (2000-06-24)
The native chemical ligation reaction has been used extensively for the synthesis of the large polypeptides that correspond to folded proteins and domains. The efficiency of the synthesis of the target protein is highly dependent on the number of peptide
M. Patek et al.
Proc. 13th Am. Peptide Symp., 146-146 (1993)

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