852473
5-Bromouracil
98%
Synonym(s):
5-Bromo-2,4-dihydroxypyrimidine
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About This Item
Empirical Formula (Hill Notation):
C4H3BrN2O2
CAS Number:
Molecular Weight:
190.98
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-084-0
Beilstein/REAXYS Number:
127176
MDL number:
Assay:
98%
Form:
crystals
Product Name
5-Bromouracil, 98%
InChI key
LQLQRFGHAALLLE-UHFFFAOYSA-N
InChI
1S/C4H3BrN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
SMILES string
BrC1=CNC(=O)NC1=O
assay
98%
form
crystals
mp
>300 °C (lit.)
functional group
bromo
Quality Level
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Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Hironobu Morinaga et al.
Bioorganic & medicinal chemistry, 21(2), 466-469 (2012-12-26)
5-Bromouracil ((Br)U) was incorporated into three types of synthetic RNA and the products of the photoirradiated (Br)U-containing RNAs were investigated using HPLC and MS analysis. The photoirradiation of r(GCA(Br)UGC)(2) and r(CGAA(Br)UUGC)/r(GCAAUUCG) in A-form RNA produced the corresponding 2'-keto adenosine ((keto)A)
Ryu Tashiro et al.
Journal of the American Chemical Society, 132(41), 14361-14363 (2010-09-30)
We have investigated the products of (Br)U in excess electron transfer and have demonstrated that in DNA the proportion of products changes with the distance between the donor and acceptor. On the basis of a labeling experiment using H(2)(18)O, we
The lesions produced by ultraviolet light in DNA containing 5-bromouracil.
F Hutchinson
Quarterly reviews of biophysics, 6(2), 201-246 (1973-05-01)
Zejun Li et al.
The journal of physical chemistry. B, 115(46), 13668-13673 (2011-09-10)
The reaction of low-energy electrons (LEEs; 10 eV) with 5'-TpXpT-3' (TXT), where X is uracil (U), thymine (T), and 5-bromouracil (5BrU), was examined by HPLC-UV analysis. The presence of 5BrU increased total damage by >50%. The radiation products of T5BrUT
Pierre Daublain et al.
The journal of physical chemistry. B, 114(45), 14265-14272 (2010-02-04)
The photophysical and photochemical behavior of a series of hairpin-forming DNA conjugates possessing a 5'-tethered pyrenecarboxamide chromophore and one or two bromouracil bases has been investigated. Quenching of the pyrene fluorescence and transient absorption spectra characteristic of the pyrene cation
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