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Merck
CN

852597

5-Iodouridine

95%

Synonym(s):

2,4-Dihydroxy-5-iodo-1-β-D-ribofuranosylpyrimidine

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About This Item

Empirical Formula (Hill Notation):
C9H11IN2O6
CAS Number:
Molecular Weight:
370.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
213-833-1
Beilstein/REAXYS Number:
33665
MDL number:
Assay:
95%
Form:
powder
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InChI key

RKSLVDIXBGWPIS-UAKXSSHOSA-N

InChI

1S/C9H11IN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=C(I)C(=O)NC2=O

assay

95%

form

powder

mp

205-207 °C (dec.) (lit.)

functional group

ether, hydroxyl, iodo

storage temp.

2-8°C

Quality Level

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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W T Stump et al.
RNA (New York, N.Y.), 1(1), 55-63 (1995-03-01)
The N-terminal RNA binding domain (RBD) of the human U1A snRNP protein binds tightly and specifically to an RNA hairpin that contains a 10-nucleotide loop. The protein is one of a class of RNA binding proteins that adopts a beta
B L Golden et al.
RNA (New York, N.Y.), 2(12), 1295-1305 (1996-12-01)
For small RNAs, isomorphous heavy-atom derivatives can be obtained by crystallizing synthetic versions that incorporate modified nucleotides such as iodo- or bromouridine. However, such a synthetic approach is not yet feasible for RNAs greater than approximately 40 nt. We have
P Martel et al.
Journal of biomolecular structure & dynamics, 12(2), 401-411 (1994-10-01)
This paper reports on the first coherent neutron scattering measurements ever carried out on the vibrational spectrum of a nucleoside analog. Frequencies up to 3.5 Thz belonging to some half-dozen dispersion curves have been measured in a plane normal to
Dehalogenation reactions in fast atom bombardment mass spectrometry.
S K Sethi et al.
Analytical chemistry, 56(11), 1975-1977 (1984-09-01)
Daniel E Ryan et al.
RNA (New York, N.Y.), 10(8), 1251-1265 (2004-07-24)
Elucidation of the three-dimensional (3D) structures of the two sequential active sites in spliceosomes is essential for understanding the mechanism of premessenger RNA splicing. The mechanism is predicted to be catalyzed by the small nuclear RNA (snRNA) components of spliceosomes.

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