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Merck
CN

855693

Sigma-Aldrich

D-Serine

99%

Synonym(s):

β-Hydroxyalanine, (R)-(−)-Serine, (R)-2-Amino-3-hydroxypropionic acid, 2-Amino-3-hydroxypropanoic acid, Ser

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About This Item

Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
105.09
Beilstein:
1721403
EC Number:
MDL number:
UNSPSC Code:
12352103
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Assay

99%

optical activity

[α]20/D −13.6°, c = 10 in 1 M HCl

mp

220 °C (dec.) (lit.)

SMILES string

N[C@H](CO)C(O)=O

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Stephan Urwyler et al.
Journal of medicinal chemistry, 52(16), 5093-5107 (2009-08-01)
Retaining agonistic activity at the glycine coagonist site of the NMDA receptor in molecules derived from glycine or d-serine has proven to be difficult because in the vicinity of the alpha-amino acid group little substitution is tolerated. We have solved
Iris Thondorf et al.
Bioorganic & medicinal chemistry, 19(21), 6409-6418 (2011-10-01)
The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitative structure-activity relationship (3D QSAR) study has been performed on its natural and synthetic
Phedias Diamandis et al.
Nature chemical biology, 3(5), 268-273 (2007-04-10)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways that governs the

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