857351
D-Glutamic acid
≥99%
Synonym(s):
(R)-2-Aminoglutaric acid, (R)-2-Aminopentanedioic acid, D-Glu, R-(−)-1-Aminopropane-1,3-dicarboxylic acid
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About This Item
Linear Formula:
HO2CCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
147.13
EC Number:
230-000-8
UNSPSC Code:
12352103
PubChem Substance ID:
Beilstein/REAXYS Number:
1723800
MDL number:
assay
≥99%
optical activity
[α]25/D −31.5°, c = 1 in 6 M HCl
mp
200-202 °C (subl.) (lit.)
SMILES string
N[C@H](CCC(O)=O)C(O)=O
InChI
1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
InChI key
WHUUTDBJXJRKMK-GSVOUGTGSA-N
Biochem/physiol Actions
Unnatural isomer of glutamic acid.
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Matthew Volgraf et al.
Nature chemical biology, 2(1), 47-52 (2006-01-13)
The precise regulation of protein activity is fundamental to life. The allosteric control of an active site by a remote regulatory binding site is a mechanism of regulation found across protein classes, from enzymes to motors to signaling proteins. We
Pierre Maechler et al.
Diabetes, 51 Suppl 1, S99-102 (2002-01-30)
It is intriguing that the kinetics of glucose-stimulated insulin secretion from the in situ perfused pancreas differ between the rat and the mouse. Here we confirm that insulin release in the rat is clearly biphasic, whereas in the mouse glucose
Jia Luo et al.
Science (New York, N.Y.), 298(5592), 425-429 (2002-10-12)
The motor abnormalities of Parkinson's disease (PD) are caused by alterations in basal ganglia network activity, including disinhibition of the subthalamic nucleus (STN), and excessive activity of the major output nuclei. Using adeno-associated viral vector-mediated somatic cell gene transfer, we