857351
D-Glutamic acid
≥99%
Synonym(s):
(R)-2-Aminoglutaric acid, (R)-2-Aminopentanedioic acid, D-Glu, R-(−)-1-Aminopropane-1,3-dicarboxylic acid
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About This Item
Linear Formula:
HO2CCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
147.13
Beilstein:
1723800
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
Assay
≥99%
optical activity
[α]25/D −31.5°, c = 1 in 6 M HCl
mp
200-202 °C (subl.) (lit.)
SMILES string
N[C@H](CCC(O)=O)C(O)=O
InChI
1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
InChI key
WHUUTDBJXJRKMK-GSVOUGTGSA-N
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Biochem/physiol Actions
Unnatural isomer of glutamic acid.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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The motor abnormalities of Parkinson's disease (PD) are caused by alterations in basal ganglia network activity, including disinhibition of the subthalamic nucleus (STN), and excessive activity of the major output nuclei. Using adeno-associated viral vector-mediated somatic cell gene transfer, we
H Persson et al.
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The gene encoding glutamic acid decarboxylase (GAD), the key enzyme in the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid, is shown to be expressed in the testis of several different species. Nucleotide sequence analysis of a cDNA clone isolated from
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