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857513

Nα-p-Tosyl-L-lysine chloromethyl ketone hydrochloride

98%

Synonym(s):

1-Chloro-3-tosylamido-7-amino-L-2-heptanone hydrochloride, TLCK hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₂₁ClN₂O₃S · HCl

CAS Number:

Molecular Weight:

369.31

UNSPSC Code:

12352103

MDL number:

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Properties

Quality Level

assay

98%

SMILES string

Cl.Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl

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High-resolution structure of the stable plasminogen activator inhibitor type-1 variant 14-1B in its proteinase-cleaved form: a new tool for detailed interaction studies and modeling.

Jan K Jensen et al.

Protein science : a publication of the Protein Society, 17(10), 1844-1849 (2008-08-30)

Wild-type plasminogen activator inhibitor type-1 (PAI-1) rapidly converts to the inactive latent state under conditions of physiological pH and temperature. For in vivo studies of active PAI-1 in cell culture and in vivo model systems, the 14-1B PAI-1 mutant (N150H-K154T-Q319L-M354I)