858579
D-Cycloserine
98%
Synonym(s):
(R)-4-Amino-3-isoxazolidone, 4-Amino-3-isoxazolidinone
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About This Item
Empirical Formula (Hill Notation):
C3H6N2O2
CAS Number:
Molecular Weight:
102.09
EC Number:
200-688-4
UNSPSC Code:
12352103
MDL number:
Beilstein/REAXYS Number:
80798
assay
98%
optical activity
[α]22/D +115°, c = 1 in H2O
mp
147 °C (dec.) (lit.)
SMILES string
N[C@@H]1CONC1=O
InChI
1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
InChI key
DYDCUQKUCUHJBH-UWTATZPHSA-N
Biochem/physiol Actions
Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic.
Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria.
Mode of Resistance: D-Ala transport interference.
Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria.
Mode of Resistance: D-Ala transport interference.
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