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Merck
CN

86020

Sulfacetamide sodium salt monohydrate

≥98.0% (dried material, T)

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About This Item

Empirical Formula (Hill Notation):
C8H9N2NaO3S · H2O
CAS Number:
Molecular Weight:
254.24
UNSPSC Code:
12352100
PubChem Substance ID:
MDL number:
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InChI

1S/C8H10N2O3S.Na.H2O/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;;/h2-5H,9H2,1H3,(H,10,11);;1H2/q;+1;/p-1

SMILES string

NC1=CC=C(S(N([Na])C(C)=O)(=O)=O)C=C1.O

InChI key

IHCDKJZZFOUARO-UHFFFAOYSA-M

assay

≥98.0% (dried material, T)

impurities

~7% water

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, mycoplasma

mode of action

enzyme | inhibits

General description

Chemical structure: sulfonamide

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Shmuel Graffi et al.
European journal of ophthalmology, 22(5), 834-835 (2012-01-24)
To report an unusual case of a patient with endogenous endophthalmitis caused by Actinomyces neuii. A 69-year-old woman in an immunosuppressed state and who had a previous history of periappendicular abscess presented with bilateral red painful eyes. The diagnosis was
Mark W Trumbore et al.
Journal of drugs in dermatology : JDD, 8(3), 299-304 (2009-03-11)
Acne rosacea is a chronic cutaneous disorder affecting as many as 14 million Americans. Papulopustular rosacea is the classic form of rosacea characterized by papules, pustules, and erythema. The skin barrier deficiency and vascular hyperactivity characteristic of papulopustular rosacea increase
Yaxian Zhen et al.
Journal of drugs in dermatology : JDD, 6(8), 810-816 (2007-09-04)
Topical therapies are effective in managing acne vulgaris but are associated with local adverse effects such as irritation and dryness. This 4-week pilot study compared skin hydration in 36 healthy adult women randomized to treatment with 1 of 4 topical
A Parodi et al.
Annales de dermatologie et de venereologie, 138 Suppl 3, S211-S214 (2012-01-04)
A range of treatment options are available in rosacea, which include several topical (mainly metronidazole, azelaic acid, other antibiotics, sulfur, retinoids) and oral drugs (mainly tetracyclines, metronidazole, macrolides). In some cases, the first choice is a systemic therapy because patients
Demet Sensoy et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 72(3), 487-495 (2009-02-19)
The aim of this study was to prepare bioadhesive sulfacetamide sodium (SA) microspheres to increase their residence time on the ocular surface and to enhance their treatment efficacy on ocular keratitis. Microspheres were fabricated by spray drying method using mixture

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