860417
Salicylamide
99%
Synonym(s):
2-Hydroxybenzamide
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About This Item
Linear Formula:
2-(HO)C6H4CONH2
CAS Number:
Molecular Weight:
137.14
Beilstein:
742439
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Quality Level
Assay
99%
form
solid
mp
140-144 °C (lit.)
SMILES string
NC(=O)c1ccccc1O
InChI
1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
InChI key
SKZKKFZAGNVIMN-UHFFFAOYSA-N
Gene Information
human ... AR(367)
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General description
Salicylamide is used as a starting material for synthesizing substituted salicylamides through acylation reactions.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Patricia D Sauzem et al.
European journal of medicinal chemistry, 43(6), 1237-1247 (2007-09-25)
In this work, we reported the synthesis and evaluation of the analgesic and anti-inflammatory properties of novel 3- or 4-substituted 5-trifluoromethyl-5-hydroxy-4,5-dihydro-1H-1-carboxyamidepyrazoles (where 3-/4-substituent=H/H, Me/H, Et/H, Pr/H, i-Pr/H, Bu/H, t-Bu/H, Ph/H, 4-Br-Ph/H and H/Me) designed in the exploration of the bioisosteric
Acylation of salicylamide to 5-acetylsalicylamide using ionic liquids as dual catalyst and solvent
Chen, W et al.
Journal of Industrial and Engineering Chemistry, 16(5), 800-804 (2010)
Yong-Jiang Zhao et al.
International journal of pharmaceutics, 379(1), 90-99 (2009-06-23)
Poly (ethylene glycol)s (PEGs) are potential drug carriers for improving the therapeutic index of anticancer agents. In this work, a novel methodology for constructing PEG prodrug of anthracycline anticancer drugs was developed based on N-Mannich base of salicylamide and its
José L Castro et al.
Langmuir : the ACS journal of surfaces and colloids, 28(24), 8926-8932 (2012-01-25)
The surface-enhanced raman scattering (SERS) of benzoic acid/benzamide and salicylic acid/salicylamide on silver colloids show important wavenumber shifts with respect to the Raman spectrum of the band assigned to mode 1;ν(ring) when adsorbed on the metal surface (ca. +50 cm(-1)).
Po-Chiao Lin et al.
Analytical chemistry, 79(9), 3401-3408 (2007-04-04)
Functionalized magnetic nanoparticles (MNPs) were synthesized to serve as laser desorption/ionization elements as well as solid-phase extraction probes for simultaneous enrichment and detection of small molecules in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis. Two laser-absorbing matrices were
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