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About This Item
Linear Formula:
2-(HO)C6H4CONH2
CAS Number:
Molecular Weight:
137.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-609-3
Beilstein/REAXYS Number:
742439
MDL number:
Assay:
99%
Form:
solid
Product Name
Salicylamide, 99%
InChI
1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
InChI key
SKZKKFZAGNVIMN-UHFFFAOYSA-N
SMILES string
NC(=O)c1ccccc1O
assay
99%
form
solid
mp
140-144 °C (lit.)
Quality Level
Gene Information
human ... AR(367)
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General description
Salicylamide is used as a starting material for synthesizing substituted salicylamides through acylation reactions.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Acylation of salicylamide to 5-acetylsalicylamide using ionic liquids as dual catalyst and solvent
Chen, W et al.
Journal of Industrial and Engineering Chemistry, 16(5), 800-804 (2010)
Po-Chiao Lin et al.
Analytical chemistry, 79(9), 3401-3408 (2007-04-04)
Functionalized magnetic nanoparticles (MNPs) were synthesized to serve as laser desorption/ionization elements as well as solid-phase extraction probes for simultaneous enrichment and detection of small molecules in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis. Two laser-absorbing matrices were
Xiaoyan Zhou et al.
Dalton transactions (Cambridge, England : 2003), 41(6), 1765-1775 (2011-12-14)
Two new flexible exo-bidentate ligands were designed and synthesized, incorporating different backbone chain lengths bearing two salicylamide arms, namely 2,2'-(2,2'-oxybis(ethane-2,1-diyl)bis(oxy))bis(N-benzylbenzamide) (L(I)) and 2,2'-(2,2'-(ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(oxy)bis(N-benzylbenzamide) (L(II)). These two structurally related ligands are used as building blocks for constructing diverse lanthanide polymers with
Jessica Nilsson et al.
Journal of inorganic biochemistry, 105(12), 1795-1800 (2011-11-08)
Reaction of N-(2-hydroxybenzyl)-N-(2-picolyl) glycine (H(2)papy) with VOSO(4) in water gives the oxidovanadium(V) oxido-bridged dimer [{(papy)(VO)}(2) μ-O)] (1). Similarly, reaction of N-(2-hydroxybenzyl) glycine (H(2)glysal) with VOSO(4) gives [(glysal)VO(H(2)O)] (2) and reaction of salicylamide (Hsalam) with VOSO(4) in methanol gives [(salam)(2)VO] (3).
Yong-Jiang Zhao et al.
International journal of pharmaceutics, 379(1), 90-99 (2009-06-23)
Poly (ethylene glycol)s (PEGs) are potential drug carriers for improving the therapeutic index of anticancer agents. In this work, a novel methodology for constructing PEG prodrug of anthracycline anticancer drugs was developed based on N-Mannich base of salicylamide and its
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