861448
8-Azaguanine
98%
Synonym(s):
2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, Guanazolo
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About This Item
Empirical Formula (Hill Notation):
C4H4N6O
CAS Number:
Molecular Weight:
152.11
EC Number:
205-148-1
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
171098
InChI
1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)
InChI key
LPXQRXLUHJKZIE-UHFFFAOYSA-N
SMILES string
NC1=Nc2[nH]nnc2C(=O)N1
assay
98%
mp
>300 °C (lit.)
Regulatory Information
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Y Xiao et al.
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 22(2), 113-115 (1997-01-01)
A human lung cancer cell line (A549) mutant with hypoxanthine guanine phosphoribosyltransferase (HGPRT) deficiency and resistance to 8-AG was established by treatment of the A549 cells with 3 micrograms.ml-1 N-methyl-N'-nitro-nitrosoguanidine (MNNG), and prescreened in 0.25% agarose DMEM semisolid medium containing
F R Ridzlan et al.
Tropical biomedicine, 27(3), 632-638 (2011-03-15)
Leptospirosis is recognized as one of the important zoonotic diseases in the world including Malaysia. A total of 145 soil and water samples were collected from selected National Service Training Centres (NSTC) in Kelantan and Terengganu. The samples were inoculated
Dong Chuan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 59(13), 3131-3137 (2003-10-30)
A comparative study, luminescence behavior of 6-Mercaptopurine (6-MP), Azathiopurine (BAN), and 8-Azaguanine (8-Azan) have been investigated including the low temperature phosphorescence, the low temperature fluorescence, the room temperature phosphorescence (RTP) and the room temperature fluorescence (RTF). The effect of pH
Bashir Mir et al.
Nucleic acids research, 32(3), e25-e25 (2004-02-13)
The use of primary somatic cells in nuclear transfer procedure has opened a new opportunity to manipulate domestic animal genomes via homologous recombination. To date, while a few loci have been targeted in somatic cells using similar enrichment strategies as
Jacek Wierzchowski et al.
Nucleosides, nucleotides & nucleic acids, 24(5-7), 459-464 (2005-10-27)
Spectroscopic and kinetic studies of interactions of calf spleen purine nucleoside phosphorylase with 8-azaguanine, an excellent fluorescent/fluorogenic substrate for the synthetic pathway of the reaction, and its 9-(2-phosphonylmethoxyethyl) derivative, a bisubstrate analogue inhibitor, were carried out. The goal was to
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