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Merck
CN

862088

Lysergol

97%

Synonym(s):

9,10-Didehydro-6-methylergoline-8β-methanol

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About This Item

Empirical Formula (Hill Notation):
C16H18N2O
CAS Number:
Molecular Weight:
254.33
UNSPSC Code:
12352200
EC Number:
210-024-5
MDL number:
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SMILES string

CN1C[C@H](CO)C=C2[C@H]1Cc3c[nH]c4cccc2c34

assay

97%

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Shrikant Patil et al.
Biomedical chromatography : BMC, 26(10), 1170-1175 (2012-01-04)
A sensitive and simple HPLC method was developed for the simultaneous quantification of berberine and lysergol in rat plasma. The chromatographic separation was achieved on a C(18) column using isocratic elution with methanol-acetonitrile-0.1% ortho-phosphoric acid (25:20:55, v/v/v), pH adjusted to
S R Gooneratne et al.
New Zealand veterinary journal, 59(5), 233-238 (2011-08-20)
To determine the effects of feeding ryegrass seed containing ergovaline to sheep selected for resistance or susceptibility to ryegrass staggers on concentration of lysergol (a metabolite of ergovaline) in urine, prolactin in plasma, rectal temperature and respiration rate. Two experiments
E M Parker et al.
Journal of neurochemistry, 67(5), 2096-2103 (1996-11-01)
5-Hydroxytryptamine elicits its physiological effects by interacting with a diverse group of receptors. Two of these receptors, the 5-HT1D beta and the 5-HT1E receptors, are approximately 60% identical in the transmembrane domains that presumably form the ligand binding site yet
Shinsuke Inuki et al.
Organic letters, 10(22), 5239-5242 (2008-10-30)
Ergot alkaloids and their synthetic analogs have been reported to exhibit broad biological activity. We investigated direct construction of the C/D ring system of ergot alkaloids based on palladium-catalyzed domino cyclization of amino allenes. With this biscyclization as the key
Shinsuke Inuki et al.
The Journal of organic chemistry, 76(7), 2072-2083 (2011-03-03)
Enantioselective total synthesis of the biologically important indole alkaloids (+)-lysergol, (+)-isolysergol, and (+)-lysergic acid is described. Key features of these total synthesis include (1) a facile synthesis of a chiral 1,3-amino alcohol via the Pd(0)- and In(I)-mediated reductive coupling reaction

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