86728
1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrayl-tetrakis(methylphosphonic acid)
≥97.0% (CHN)
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About This Item
Empirical Formula (Hill Notation):
C12H32N4O12P4
CAS Number:
Molecular Weight:
548.30
Beilstein:
3579556
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Assay
≥97.0% (CHN)
SMILES string
OP(O)(=O)CN1CCN(CCN(CCN(CC1)CP(O)(O)=O)CP(O)(O)=O)CP(O)(O)=O
Other Notes
Complexing agent. Lanthanide complexes are used as NMR shift reagents; Complexation properties with earth-alkali ions
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Anupama Datta et al.
Cancer biotherapy & radiopharmaceuticals, 24(1), 123-128 (2009-02-27)
The convenient synthetic methodology and in vivo stability of the bone-seeking gamma-radiation-emitting compound, (99m)Tc-DOTMP are described in this paper. The radiolabeling efficiency was found to be >97%, and the stability in serum indicated that (99m)Tc remained bound to the chelate
Ferenc K Kálmán et al.
Inorganic chemistry, 47(9), 3851-3862 (2008-04-03)
A cyclen-based ligand containing trans-acetate and trans-methylenephosphonate pendant groups, H 6DO2A2P, was synthesized and its protonation constants (12.6, 11.43, 5.95, 6.15, 2.88, and 2.77) were determined by pH-potentiometry and (1)H NMR spectroscopy. The first two protonations were shown to occur
D.W. Swinkels et al.
Rec. Trav. Chim., 110, 124-124 (1991)
J P Van Duynhoven et al.
European journal of biochemistry, 216(2), 507-517 (1993-09-01)
Scrutiny of NOE data available for the protein encoded by gene V of the filamentous phage IKe (IKe GVP), resulted in the elucidation of a beta-sheet structure which is partly five stranded. The DNA-binding domain of IKe GVP was investigated
Naoto T Ueno et al.
Clinical breast cancer, 9(3), 173-177 (2009-08-08)
Bone-targeted radiation therapy is an attractive strategy for addressing bone disease with minimal systemic toxicity. This pilot study was designed to determine the safety and efficacy of (166)Holmium (Ho)-DOTMP for irradiating malignant cells and adjacent marrow in women with bone-only
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