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900210

Regenerez® Poly(glycerol sebacate) Resin

Synonym(s):

PGS, Poly(glycerol sebacic acid)

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About This Item

Linear Formula:
(C13H22O5)n
UNSPSC Code:
12352200
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form

paste

Quality Level

100

transition temp

flash point >230 °F

storage temp.

−20°C

Application

Regenerez® Poly(glycerol sebacate) is a bioresorbable elastomer. The physical properties can be tuned from an elastomer to a thermoset(U.S. Patent No. 9.359,472) by curing PGS to the desired level of cross-linking. The inherent elastomeric properties of PGS can be used in a variety of applications in regenerative medicine and tissue engineering.

Features and Benefits

  • Bioresorbable.
  • Comprised of naturally occurring metabolites (glycerol and sebacic acid).
  • Tunable mechanical properties.
  • Versatile platform for further modification.
  • Closely simulates modulus of human tissue.
  • Enables healing without harmful immune response.

Legal Information

U.S. Patent No. 9,359,472.
Regenerez is a registered trademark of The Secant Group, LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available

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Certificates of Analysis (COA)

Lot/Batch Number
MKBZ6740

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Samer H Zaky et al.
Biomedical materials (Bristol, England), 9(2), 025003-025003 (2014-02-04)
For bone engineering, the optimal scaffolding material and composition has yet to be elucidated. In this study, we investigated poly (glycerol sebacate) (PGS), an elastomer known primarily for its soft tissue regeneration ability, as a suitable substrate to support osteo-precursor
Qi-Zhi Chen et al.
Journal of the mechanical behavior of biomedical materials, 4(8), 1805-1818 (2011-11-22)
Poly (glycerol sebacate) (PGS) is a promising elastomer for use in soft tissue engineering. However, it is difficult to achieve with PGS a satisfactory balance of mechanical compliance and degradation rate that meet the requirements of soft tissue engineering. In
Wei Wu et al.
Nature medicine, 18(7), 1148-1153 (2012-06-26)
Host remodeling is important for the success of medical implants, including vascular substitutes. Synthetic and tissue-engineered grafts have yet to show clinical effectiveness in arteries smaller than 5 mm in diameter. We designed cell-free biodegradable elastomeric grafts that degrade rapidly
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