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Merck
CN

900629

Gelatin methacryloyl

gel strength 300 g Bloom, degree of substitution 40%

Synonym(s):

GelMa, Gelatin Methacrylate, Gelatin methacrylamide, Gelatin / GelMA & derivatives

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About This Item

Linear Formula:
(C40H59N11O13)n
NACRES:
NA.23
UNSPSC Code:
12352202
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Quality Level

form

powder

storage temp.

2-8°C

Application

Gelatin-methacrylate can be used to form crosslinked hydrogels for tissue engineering and 3D printing. It has been used for endothelial cell morphogenesis, cardiomyocytes, epidermal tissue, injectable tissue constructs, bone differentiation, and cartilage regeneration. Gelatin-methacrylate has been explored in drug delivery applications in the form of microspheres and hydrogels.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

动物来源培养基

This item has



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Articles

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.

Discover hydrogels, biocompatible materials for drug delivery, tissue engineering, wound care, and 3D bioprinting in innovative biomedical applications


Preparation and characterization of gelatin-poly(methacrylic acid) interpenetrating polymeric network hydrogels as a pH-sensitive delivery system for glipizide.
Gupta NV et al.
Indian Journal of Pharmaceutical Sciences, 69(1), 64-68 (2007)
Xin Zhao et al.
Advanced healthcare materials, 5(1), 108-118 (2015-04-17)
Natural hydrogels are promising scaffolds to engineer epidermis. Currently, natural hydrogels used to support epidermal regeneration are mainly collagen- or gelatin-based, which mimic the natural dermal extracellular matrix but often suffer from insufficient and uncontrollable mechanical and degradation properties. In
Anh H Nguyen et al.
Acta biomaterialia, 13, 101-110 (2014-12-03)
Gelatin has been commonly used as a delivery vehicle for various biomolecules for tissue engineering and regenerative medicine applications due to its simple fabrication methods, inherent electrostatic binding properties, and proteolytic degradability. Compared to traditional chemical cross-linking methods, such as



Global Trade Item Number

SKUGTIN
900629-5G04065267536194
900629-1G04061824070613