900721
Bovine fibrillar collagen solution
type I, 65 mg/mL, pH 7.0, suitable for biomedical research
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About This Item
CAS Number:
UNSPSC Code:
12352200
biological source
bovine
description
% Denatured: ≤15%
Collagen concentration (by biruret method): 6.0 - 7.0%
Electrophoretic pattern (purity by SDS PAGE): ≤10% collagen faster than alpha.
form
solution
shelf life
24 mo. (from date of manufacture)
concentration
65 mg/mL
impurities
<0.25 EU/mL Endotoxin
pH
7.0-7.6
7.0
storage temp.
2-8°C
General description
Bovine fibrillar collagen solution is a highly concentrated (65 mg/mL) Type I collagen solution that can easily be diluted as needed with media or buffer solutions. This material features high purity (purification through pepsin treatment) which offers reduced antigenicity with the removal of possible contaminants and is provided at neutral pH (pH 7.0). In vivo, fibrillar collagen degrades in approximately 30 days.
Application
Collagen is a major structural protein that provides structure and strength to tissues in the body. Due to its biocompatibility, biodegradability, and high abundance, collagen has been utilized for many applications in biomedical research. Applications of fibrillar collagen may include:
- Development of collagen-based tissues for skin replacement, bone substitutes, and to generate artificial blood vessels and valves.
- Drug delivery systems such as sponges for burns/wounds, formulations with liposomes for sustained drug delivery, materials for transdermal drug delivery, and nanoparticles for gene delivery.
- As collagen scaffolds for research in cancer, electrophysiological protocols, neuron myelination, immunology, and other cell culture applications.
Analysis Note
Appearance: White or off-white viscous gel (paste).
Legal Information
Product of Collagen Solutions.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
动植物来源生物产品
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