901333
Bis-MPA-NHBoc dendrimer
trimethylol propane core, generation 1
Synonym(s):
Bis-MPA dendrimer, NHBoc functionalized dendrimer, PFD-G1-TMP-NH-BOC
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About This Item
Empirical Formula (Hill Notation):
C69H116N6O30
Molecular Weight:
1509.68
UNSPSC Code:
12162002
NACRES:
NA.23
form
solid or viscous liquid
mol wt
generation 1
no. Surface Groups
6
color
colorless to pale yellow
storage temp.
−20°C
General description
- Polymer architecture: Dendrimer
- Generation: 1
- End Group Functionality: Boc-protected amine
- No. Surface Groups: 6
- Calculated Mol. Wt.: 1509.70 g/mol
- Boc : tert-Butyloxycarbonyl
- Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid.
Application
Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrimers synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. After Boc deprotection, amine-functionalized dendrimers can be readily used in EDC or DCC coupling reactions with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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