901459
Allyl poly(ethylene glycol)-block-poly(lactide-co-glycolide)
PEG average Mn 5000, PLGA average Mn 15000, lactide:glycolide (50:50)
Synonym(s):
Allyl-PEG-b-PLGA, Allyl-PEG-PLGA
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
C3H5O(C2H4O)n[(C2H2O2)x(C3H4O2)y]m
NACRES:
NA.23
UNSPSC Code:
51171641
description
Feed Ratio: 50:50+/-5 (Lactide:Glycolide, by NMR), Identity: Conforms to structure (by NMR)
form
powder
feed ratio
lactide:glycolide (50:50), lactide:glycolide±5 (50:50)
mol wt
PEG Mn 4000-6000 g/mol (NMR), PEG average Mn 5000, PLGA Mn 13500-16500 g/mol (NMR), PLGA average Mn 15000
color
white
storage temp.
−20°C
Application
Allyl poly(ethylene glycol)-block-poly(lactide-co-glycolide) is an allyl-functionalized, biocompatible, amphiphilic block copolymer. Due to its self-assembling properties, this material can be used in the formation of nanoparticles for drug delivery. Additionally, due to the allyl-functionalization of the PEG block, this material can be used to covalently conjugate biomolecules, API, or targeting ligands rapidly. Potential uses include the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anaesthetic agents.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
>230.9 °F
flash_point_c
> 110.5 °C
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Biodegradable PLGA-b-PEG polymeric nanoparticles: synthesis, properties and nanomedical applications as drug delivery system.
Locatelli E, et al.
Journal of Nanoparticle Research, 14, 1316-1316 (2012)
Polymer degradation and drug delivery in PLGA-based drug-polymer applications: A review of experiments and theories.
Xu Y, et al.
Journal of Biomedical Materials Research. Part B, Applied Biomaterials, 105, 1692-1716 (2017)
Biodegradable PLGA-b-PEG polymeric nanoparticles: synthesis, properties and nanomedical applications as drug delivery system
Locatelli E, et al
Journal of Nanoparticle Research, 14, 1316-1316 (2012)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 901459-1G | 04061834898887 |