901588
1,3-Propanesultone solution
1 M in THF
Synonym(s):
1,2-Oxathiolane 2,2-dioxide, 3-Hydroxypropanesulfonic acid γ-sultone
InChI
1S/C3H6O3S/c4-7(5)3-1-2-6-7/h1-3H2
InChI key
FSSPGSAQUIYDCN-UHFFFAOYSA-N
form
liquid
concentration
1 M in THF
refractive index
n/D 1.4144
density
0.9266 g/mL
Application
1,3-Propanesultone has been used in:
- preparation of poly[2-ethynyl-N-(propylsulfonate)pyridinium betaine], a new ionic conjugated polymer
- preparation of novel poly(4-vinylpyridine) supported acidic ionic liquid catalyst
- preparation of poly((2-(dimethylamino)ethyl methacrylate)-co-3-dimethyl(methacryloyloxyethyl)ammonium propanesulfonate)-coated mesoporous silica nanoparticles
- sulfonation of surface of self-assembled nanoporous silica colloidal crystalline films comprised of 184nm-diameter silica spheres
Valuable building block or solvent offered as a solution in tetrahydrofuran for more convenient handling.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Central nervous system, Respiratory system
supp_hazards
Storage Class
3 - Flammable liquids
wgk
WGK 3
flash_point_f
-2.0 °F
flash_point_c
-18.88 °C
Regulatory Information
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Junke Wang et al.
Ultrasonics sonochemistry, 21(1), 29-34 (2013-06-12)
A novel poly(4-vinylpyridine) supported acidic ionic liquid catalyst was synthesized by the reaction of 4-vinylpyridine with 1,3-propanesultone, followed by the polymerization and the addition of the heteropolyacid. Due to the combination of polymer features and ionic liquid, it acted as
Yeong-Soon Gal et al.
Journal of nanoscience and nanotechnology, 14(7), 5480-5484 (2014-04-25)
A new ionic conjugated polymer was prepared by the activated polymerization of 2-ethynylpyridine with the ring-opening of 1,3-propanesultone without any additional initiator or catalyst. This polymer was characterized by various instrumental methods to have conjugated polymer backbone system with pendant
D K Torous et al.
Mutation research, 465(1-2), 91-99 (2000-03-10)
Micronuclei (MN) are routinely enumerated in mouse peripheral blood to index genotoxicity. Recent data from the Collaborative Study Group for the Micronucleus Test (CSGMT) [CSGMT (The Collaborative Study Group for the Micronucleus Test), Evaluation of the rat micronucleus test with
1,3-Propane sultone, an extremely potent experimental carcinogen: what should be expected in humans?
Hermann M Bolt et al.
Toxicology letters, 151(1), 251-254 (2004-06-05)
1,3-Propane sultone is directly alkylating, genotoxic and carcinogenic. In rats, it induces local and systemic tumours at multiple target sites. Preponderant systemic tumours occur at the central nervous system, especially gliomas. Other localisations include the mammary gland, the intestine, the
B L Kaul et al.
Mutation research, 89(1), 57-61 (1981-05-01)
The effects of three phenolic antioxidants, butylated hydroxyanisole, butylated hydroxytoluene and propyl gallate on the mutagenic activity of propane sultone were studied using barley as the test system. The antioxidants produced seedling injury marginally but did not produce any chromosomal
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