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901606

tert-Butyl carbazate solution

1.0 M in dichloromethane

Synonym(s):

tert-Butoxycarbonyl hydrazide, tert-Butyl hydrazinecarboxylate, Boc-hydrazide

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About This Item

Linear Formula:
C5H12N2O2
CAS Number:
UNSPSC Code:
12352108
MDL number:
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form

liquid

reaction suitability

reactivity: amine reactive, reagent type: protection reagent

concentration

1.0 M in dichloromethane

refractive index

n/D 1.427

density

1.290 g/mL

functional group

amine, hydrazine

InChI

1S/C5H12N2O2/c1-5(2,3)9-4(8)7-6/h6H2,1-3H3,(H,7,8)

InChI key

DKACXUFSLUYRFU-UHFFFAOYSA-N

Application

Employed in a palladium-catalyzed cross-coupling with vinyl halides leading to N-Boc-N-alkenylhydrazines.
Reagent used in solid phase peptide synthesis and in α-amino aldehyde optical purity determinations. Condenses with aldehydes to form hydrazones which are intermediates in the synthesis of HIV-1 protease inhibitors.


pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3



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