907723
Azide functionalized gelatin
degree of substitution >80%
Synonym(s):
Azide functionlized gelatin, Azide-modified gelatin, Clickable gelatin, Gelatin / GelMA & derivatives
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About This Item
NACRES:
NA.23
UNSPSC Code:
12352125
description
Degree of substitution: greater than 80% by TNBS method, NMR: Conforms to structure
form
powder
color
white to pale yellow
storage temp.
−20°C
General description
Due to its biodegradablity and biocompatibility, gelatin is routinely used in hydrogels for biomedical applications such as drug delivery, tissue engineering, and 3D bioprinting. Gelatin-based hydrogels are synthesized by the crosslinking of functionalized gelatins. Depending on the identity of the functional groups, several different processes can be used to synthesize crosslinked gelatin hydrogels, including radical-based (either thermal or photochemical) and click chemistry methods. Azide-functionalized gelatin can be used in the synthesis of hydrogels using click chemistry with alkyne-containing substrates.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
监管及禁止进口产品
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Gelatin hydrogels via thiol-ene chemistry
Russo L, et al.
Monatshefte fur Chemie / Chemical Monthly, 147, 587-592 (2016)
Thiol-yne `click?/coupling chemistry and recent applications in polymer and materials synthesis and modification.
Andrew B. Lowe
Polymer, 55 (2014)
Sandeep T Koshy et al.
Advanced healthcare materials, 5(5), 541-547 (2016-01-26)
Injectable gelatin hydrogels formed with bioorthogonal click chemistry (ClickGel) are cell-responsive ECM mimics for in vitro and in vivo biomaterials applications. Gelatin polymers with pendant norbornene (GelN) or tetrazine (GelT) groups can quickly and spontaneously crosslink upon mixing, allowing for
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 907723-1G | 04022536049786 |