914169
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) dimethacrylate
average Mn ~12,500
Synonym(s):
PEG-PPG-PEG, Pluronic Dimethacrylate, Pluronic F-127 dimethacrylate, block-copolymers
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About This Item
Linear Formula:
C4H5O[C2H4O]x[C3H6O]y[C2H4O]zC4H5O2
NACRES:
NA.23
UNSPSC Code:
12162002
Application
Poloxamers are nonionic, triblock copolymers containg a central hydrophobic chain of poly(propylene glycol) (PPG) and two terminal hydrophilic chains of poly(ethylene glycol) (PEG). Due to their amphiphilic structure, poloxamer solutions feature temperature dependent self-assembling and thermo-gelling behavior. Concentrated aqueous solutions of poloxamers are liquid at low temperature and form a gel at higher temperature, in a reversible process. This characteristic has allowed for these materials to be used as drug carriers for most routes of administration including oral, topical, intranasal, ocular, and parenteral. Methacrylate-modified derivatives are most commonly used as thermosensitive hydrogels for drug delivery and 3D bioprinting applications. After casting or printing, the material can be crosslinked to preserve the hydrogel structure.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Photopolymerization of Pluronic F127 diacrylate: a colloid-templated polymerization.
Biase M D, et al.
Soft Materials, 7, 4928-4937 (2011)
Self-Assembly of Pluronic F127 Diacrylate in Ethylammonium Nitrate: Structure, Rheology, and Ionic Conductivity before and after Photo-Cross-Linking.
Barron C R L, et al.
Macromolecules, 49(14), 5179-5189 (2016)
Christopher J Hansen et al.
Advanced materials (Deerfield Beach, Fla.), 25(1), 96-102 (2012-10-31)
Microvascular multinozzle arrays are designed and fabricated for high-throughput printing of functional materials. Ink-flow uniformity within these multigeneration, bifurcating microchannel arrays is characterized by computer modeling and microscopic particle image velocimetry (micro-PIV) measurements. Both single and dual multinozzle printheads are
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 914169-1G | 04061842093229 |
| 914169-5G | 04061842093236 |