Skip to Content
Merck
CN

924474

Hyaluronic Acid

Low Viscosity, Low endotoxin

Synonym(s):

3D bioprinting, HA, Hyaluronan

Sign In to View Organizational & Contract Pricing

Select a Size

About This Item

UNSPSC Code:
12352201
NACRES:
NA.23

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

100

form

(powder or chunk(s) or fibers)

impurities

<10 CFU/g Bioburden
<100 EU/g Endotoxin

color

white to off-white

suitability

conforms to structure for NMR

storage temp.

2-8°C

General description

Hyaluronic acid (HA) is a linear polysaccharide of alternating D-glucuronic acid, and N-acetyl-D-glucosamine found in the extracellular matrix. HA is commonly chemically modified to form covalently crosslinked hydrogels. Other properties of HA include cell surface receptors CD44 and RHAMM recognition and degradation via hyaluronidases.

Application

HA is increasingly used for the following biomedical applications:
  • Cell migration
  • Angiogenesis
  • Viability
  • Proliferation

Our low endotoxin HA is tested for both endotoxin (< 100 EU/g) and bioburden (< 10 CFU/g) levels, so you can choose which material is right for your research.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCX0943
MKCW6195
MKCW4277
MKCW0813
MKCV7589

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Tracey J Brown
Current pharmaceutical biotechnology, 9(4), 253-260 (2008-08-12)
Despite advances in chemotherapeutic regimens, the treatment of metastatic cancer remains a challenge. A key problem with chemotherapy drugs is nonspecific drug distribution, resulting in low tumor concentrations and systemic toxicity. The holy grail of clinical cancer research has been
Xian Xu et al.
Soft matter, 8(12), 3280-3294 (2012-03-16)
Hyaluronic acid (HA) is one of nature's most versatile and fascinating macromolecules. Being an essential component of the natural extracellular matrix (ECM), HA plays an important role in a variety of biological processes. Inherently biocompatible, biodegradable and non-immunogenic, HA is
Federica Camin et al.
Journal of agricultural and food chemistry, 58(1), 570-577 (2009-12-17)
H, C, and O stable isotope ratios and the elemental profile of 267 olive oils and 314 surface waters collected from 8 European sites are presented and discussed. The aim of the study was to investigate if olive oils produced
Kevin T Dicker et al.
Acta biomaterialia, 10(4), 1558-1570 (2013-12-24)
Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the extracellular matrix (ECM), on the cell surface and even inside cells. Being a simple polysaccharide, HA exhibits
Jason A Burdick et al.
Advanced materials (Deerfield Beach, Fla.), 23(12), H41-H56 (2011-03-12)
Hyaluronic acid (HA), an immunoneutral polysaccharide that is ubiquitous in the human body, is crucial for many cellular and tissue functions and has been in clinical use for over thirty years. When chemically modified, HA can be transformed into many

Articles

Rational Design of ECMs Toward Cancer Immunotherapy

Engineered ECMs enhance immune therapy in cancer treatment by supporting cells and tissues and modulating immune response. They improve immune cell maturation, expansion, and regulation through biomaterial manipulation, acting as frameworks or carriers for enhanced tumor immunotherapy.

Hydrogels for Biomedical Applications

Discover hydrogels, biocompatible materials for drug delivery, tissue engineering, wound care, and 3D bioprinting in innovative biomedical applications

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service