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Merck
CN

92664

3,6-Dihydroxyphthalonitrile

Synonym(s):

2,3-Dicyano-1,4-hydroquinone, 2,3-Dicyanohydroquinone, DCH

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About This Item

Empirical Formula (Hill Notation):
C8H4N2O2
CAS Number:
Molecular Weight:
160.13
PubChem Substance ID:
UNSPSC Code:
12352100
Beilstein/REAXYS Number:
2101249
MDL number:
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SMILES string

Oc1ccc(O)c(C#N)c1C#N

InChI

1S/C8H4N2O2/c9-3-5-6(4-10)8(12)2-1-7(5)11/h1-2,11-12H

InChI key

MPAIWVOBMLSHQA-UHFFFAOYSA-N


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R A Star et al.
The American journal of physiology, 253(6 Pt 2), F1232-F1242 (1987-12-01)
The present study was carried out to test directly whether isolated perfused rabbit cortical collecting ducts (CCDs) spontaneously generate a luminal disequilibrium pH. We determined disequilibrium pH as the difference between 1) the actual luminal pH measured by perfusing the
I Kurtz et al.
Biophysical journal, 48(3), 499-508 (1985-09-01)
We have developed new methodology for measuring intracellular pH (pHi) in cultured cell monolayers and epithelia by analyzing the emission spectra of the trapped fluorescent pH probe, 1,4-dihydroxyphthalonitrile (1,4-DHPN). This compound is unique since both its acid and base forms
P D Jöbsis et al.
Journal of microscopy, 217(Pt 3), 260-264 (2005-02-24)
The use of 2,3-dicyanohydroquinone (DCHQ) as an emission ratiometric probe of pH in vitro and in fibroblast cells was evaluated using two-photon excitation fluorescence microscopy (TPEFM). In addition, methods for spectrally calibrating the Zeiss LSM510 META spectroscopy system for TPEFM
J I Gillespie et al.
The Journal of physiology, 405, 385-395 (1988-11-01)
1. Measurements of intracellular pH (pHi) have been made using the fluorescent dye dicyano-hydroquinone (DCH) in somites isolated from 2-day-old chick embryos. Measurements of pHi, from freshly dissected somites, gave values of 7.18 +/- 0.02 (mean +/- S.D., n =
Fast intracellular pH determination in single cells by flow-cytometry.
G Valet et al.
Die Naturwissenschaften, 68(5), 265-266 (1981-05-01)

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