927538
AlkFAA-alkyne
≥95%
Synonym(s):
2-Fluoro-N-(hex-5-yn-1-yl)acrylamide
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About This Item
Empirical Formula (Hill Notation):
C9H12FNO
Molecular Weight:
169.20
MDL number:
UNSPSC Code:
12352101
NACRES:
NA.21
Assay:
≥95%
Form:
semisolid
Quality Level
Assay
≥95%
form
semisolid
storage temp.
−20°C
SMILES string
O=C(NCCCCC#C)C(F)=C
InChI
1S/C9H12FNO/c1-3-4-5-6-7-11-9(12)8(2)10/h1H,2,4-7H2,(H,11,12)
InChI key
OYWMWMCPHAXPHY-UHFFFAOYSA-N
Application
AlkFAA-alkyne is a Michael acceptor probe that was designed to label cysteines, but is not very effective. The compound can be used as a negative control when run with other cysteine-reactive probes. A method was developed using cysteine-reactive compounds to allow for unbiased analysis of proteomic data in quantitative applications . The method uses light or heavy labeling with the isotopically labelled desthiobiotin azide (isoDTB) tag for mass spectrometry analysis . Analysis then uses the isotopic tandem orthogonal proteolysis activity-based protein profiling (isoTOP-ABPP) workflow
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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