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92855

Glycerol trienanthate

Name: Glycerol trienanthate
Brand: ALDRICH

≥94%

Synonym(s):

1,2,3-Trienanthoylglycerol, Glycerol triheptanoate, Triheptanoin, Trioenanthin

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About This Item

Linear Formula:

[CH₃(CH₂)₅COOCH₂]₂CHOCO(CH₂)₅CH₃

CAS Number:

620-67-7

Molecular Weight:

428.60

EC Number:

210-647-2

UNSPSC Code:

12352100

PubChem Substance ID:

57653497

Beilstein/REAXYS Number:

1807724

MDL number:

MFCD00042910

Assay:

≥94% (TLC), ≥94%

Form:

liquid

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Properties

assay

≥94% (TLC), ≥94%

form

liquid

refractive index

n20/D 1.444

density

0.966 g/mL at 20 °C (lit.)

SMILES string

CCCCCCC(OCC(COC(CCCCCC)=O)OC(CCCCCC)=O)=O

InChI

1S/C24H44O6/c1-4-7-10-13-16-22(25)28-19-21(30-24(27)18-15-12-9-6-3)20-29-23(26)17-14-11-8-5-2/h21H,4-20H2,1-3H3

InChI key

PJHKBYALYHRYSK-UHFFFAOYSA-N

Description

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

404.6 °F - open cup

flash_point_c

207 °C - open cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Ketogenic and anaplerotic dietary modifications ameliorate seizure activity in Drosophila models of mitochondrial encephalomyopathy and glycolytic enzymopathy.

Keri J Fogle et al.

Molecular genetics and metabolism, 126(4), 439-447 (2019-01-27)

Seizures are a feature not only of the many forms of epilepsy, but also of global metabolic diseases such as mitochondrial encephalomyopathy (ME) and glycolytic enzymopathy (GE). Modern anti-epileptic drugs (AEDs) are successful in many cases, but some patients are

Triheptanoin for glucose transporter type I deficiency (G1D): modulation of human ictogenesis, cerebral metabolic rate, and cognitive indices by a food supplement.

Juan M Pascual et al.

JAMA neurology, 71(10), 1255-1265 (2014-08-12)

Disorders of brain metabolism are multiform in their mechanisms and manifestations, many of which remain insufficiently understood and are thus similarly treated. Glucose transporter type I deficiency (G1D) is commonly associated with seizures and with electrographic spike-waves. The G1D syndrome

A pilot study of add-on oral triheptanoin treatment for children with medically refractory epilepsy.

Sophie Calvert et al.

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 22(6), 1074-1080 (2018-08-22)

Despite antiepileptic medication and dietary treatment options available about 45% of children with epilepsy still suffer from uncontrolled seizures. Triheptanoin is an anaplerotic treatment designed to improve energy generation via the Krebs cycle. For the first time, we evaluated the

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Global Trade Item Number

SKU	GTIN
92855-5ML	04061837502187
92855-25ML	04061837502170