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Merck
CN

929832

Sigma-Aldrich

PCL-PEG-PCL diacrylate

average Mn (600-6000-600), poly(caprolactone)-b-poly(ethylene glycol)-b-poly(caprolactone) diacrylate

Synonym(s):

PCL-b-PEG-b-PCL, PEG hydrogel, acrylate-PCL-PEG-PCL-acrylate, biodegradable triblock copolymer

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About This Item

Linear Formula:
C2H3O2(C6H10O2)x(C2H4O)y(OC6H10O)zOC2H3
UNSPSC Code:
12352200
NACRES:
NA.25

Key Documents

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Quality Level

100

form

low-melting solid

mol wt

average Mn (600-6000-600)

contains

contains ≤ 300 ppm MEHQ as inhibitor

color

white to off-white

Ω-end

acrylate

α-end

acrylate

storage temp.

−20°C

SMILES string

O=C(OCCOC(CCCCCOC(C=C)=O)=O)CCCCCOC(C=C)=O

InChI key

PCLZPCUCIICUMZ-UHFFFAOYSA-N

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General description

PCL-PEG-PCL diacrylate, average Mn 600-6000-600, is a functionalized, amphiphilic triblock copolymer composed of a central hydrophilic, biocompatible poly(ethylene glycol) (PEG) block and two terminal hydrophobic, biodegradable poly(caprolactone) (PCL) blocks. PCL-PEG-PCL diacrylate can be crosslinked via free radical polymerization and/or photopolymerization to form a crosslinked hydrogel network. Hydrolysis of the esters of the PCL blocks permits degradation of the crosslinked networks.

Application

  • Tissue engineering
  • 3D printing
  • Drug delivery

Features and Benefits

  • PCL-PEG-PCL triblock copolymer
  • Hydrolytically degradable PCL blocks
  • Acrylate functional groups permit photopolymerization

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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