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930741

Poly(oligoethylene glycol methacrylate)

Synonym(s):

POEGMA, Poly(oligo(ethylene glycol)methacrylate)

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About This Item

Linear Formula:
C6H8NO2[C4H5O2(C2H4O)x]nOH
NACRES:
NA.21
UNSPSC Code:
12352104
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form

liquid

Quality Level

100

mol wt

80,000-130,000

color

colorless

storage temp.

−20°C

General description

Poly(oligo(ethylene glycol) methacrylate) (POEGMA) is a family of polymers consisting of a hydrophobic methacrylate backbone and hydrophilic ethylene oxide (EO) side groups with highly branched architecture. The highly branched architecture with a high density of oligo EO moities enhances the solubility of the polymer in water.

Application

Poly(oligo(ethylene glycol) methyl ether methacrylate) (POEGMA) is a family of polymers consisting of a hydrophobic methacrylate backbone and hydrophilic ethylene oxide (EO) side groups with highly branched architecture . The side chain EO segments enhance the solubility of the polymer in water , exhibiting many interesting properties such as non-fouling , stealth, anti-PEG antibodies & thermo-responsive behaviors.
  • Drug delivery- enhances the stability and delivery of siRNA and eliminates PEG antigenicity
  • Biosensor coatings- provides an anti-fouling surface
  • Stimuli-responsive hydrogels for tissue engineering, drug delivery, and other biomedical applications

Features and Benefits

  • Highly branched architecture and high density of oligo ethylene oxide moieties
  • Water soluble
  • Nonfouling and thermo-responsive behaviors
  • Viable alternative to PEG in biological and biomaterial applications

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKCS2288

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Rafael Pires-Oliveira et al.
Langmuir : the ACS journal of surfaces and colloids, 36(49), 15018-15029 (2020-12-05)
Understanding of the temperature-induced phase transition of poly(oligo(ethylene glycol) methyl ether methacrylate) (POEGMA) random copolymers with varied composition remains largely incomplete. Upon heating they can form either macroscopically phase-separated aggregates or micelles. We examined the effect of polymer architecture by
In Pursuit of Zero 2.0: Recent Developments in Nonfouling Polymer Brushes for Immunoassays
Heggestad J., et al.
Advanced Materials, 32 (2020)
(Co)polymers of oligo(ethylene glycol) methacrylates?temperature-induced aggregation in aqueous solution.
Trzebicka B, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 51, 614?623-614?623 (2013)
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Global Trade Item Number

SKUGTIN
930741-1G04065268917312