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936391

Fmoc-Gly-Gly-OH

Name: Fmoc-Gly-Gly-OH
Brand: ALDRICH

≥95%

Synonym(s):

2-[2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)acetamido]acetic acid, N-9-Fluorenylmethoxycarbonylglycylglycine, N-Fluorenylmethoxycarbonylglycylglycine, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycylglycine (ACI), Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycyl- (9CI, ACI), Glycine, N-[N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycyl]- (ZCI)

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About This Item

Empirical Formula (Hill Notation):

C₁₉H₁₈N₂O₅

CAS Number:

35665-38-4

Molecular Weight:

354.36

UNSPSC Code:

12352106

NACRES:

NA.22

MDL number:

MFCD00190880

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Properties

Quality Level

100

assay

≥95%

form

powder or crystals

color

white to off-white

storage temp.

2-8°C

SMILES string

O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NCC(=O)NCC(=O)O

InChI

1S/C19H18N2O5/c22-17(20-10-18(23)24)9-21-19(25)26-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2,(H,20,22)(H,21,25)(H,23,24)

InChI key

FBKUOPULLUJMOC-UHFFFAOYSA-N

Description

Application

Fmoc-Gly-Gly-OH is a lysosomally cleavable linker used in construction of antibody-drug conjugates (ADC & Bioconjugation).

Other Notes

Chemical Biology Tools

http://pubs.rsc.org/en/Content/ArticleLanding/2011/MB/C0MB00074D#!divAbstract

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Strategies and challenges for the next generation of antibody-drug conjugates.

Alain Beck et al.

Nature reviews. Drug discovery, 16(5), 315-337 (2017-03-18)

Antibody-drug conjugates (ADCs) are one of the fastest growing classes of oncology therapeutics. After half a century of research, the approvals of brentuximab vedotin (in 2011) and trastuzumab emtansine (in 2013) have paved the way for ongoing clinical trials that

Global Trade Item Number

SKU	GTIN
936391-100MG	04065270731012
936391-50MG	04065270731029

Key Documents

Fmoc-Gly-Gly-OH

≥95%

Select a Size

About This Item

Quality Level

assay

form

color

storage temp.

SMILES string

InChI

InChI key

Application

Other Notes

Safety Information

Storage Class

wgk

flash_point_f

flash_point_c

Regulatory Information

Documentation

Certificates of Analysis (COA)

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Peer Reviewed Papers

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