940488
TissueFab® bioink DLP
synthetic, Vis/405nm
Synonym(s):
3D bioprinting, Digital light processing
Quality Level
form
powder
quality
Endotoxin: < 100 EU/g
Bioburden: < 10 CFU/g
composition
contains photoabsorber
color
yellow to orange
application(s)
3D bioprinting (DLP)
compatibility
cell culture, 3D bioprinting
storage temp.
−20°C
Related Categories
General description
Rethink your bioinks with TissueFab®
About the material:
The low endotoxin TissueFab® DLP bioink, synthetic, Vis/405nm contains:
*Low endotoxin, xeno-free, synthetic bioink precursor
*UV photoabsorber
Printing and crosslinking parameters:
*Suitable for DLP bioprinting
* Photoinitiator-assisted crosslinking at 405nm wavelength (Visible light)
The TissueFab® bioink DLP is a xeno-free, synthetic bionk used for DLP 3D bioprinting applications. This bioink is free of animal derived components, and offers batch-to-batch consistency with minimal risk of contamination (ie. bioburden or endotoxin). The TissueFab® bioink DLP is an effective bioink for fabricating cell-encapsulated scaffolds with sutiable microenvrionmental conditions for tissue engineering and regenerative medicine applications. This bioink photopolymerizes rapidly by mixing with the Ruthenium photoinitiator kit (916881) to create high resolution hydrogels with structural integrity. This xeno-free synthetic bioink is biocompatible, biodegradable, and promotes cellular function. Digital Light Processing (DLP) bioprinting is a 3D printing technology that uses projected light to selectively cure or harden photpolymer resins layer by layer to create three-dimensional (3D) objects. DLP is well known for its printing speed and precision. Compared to extrusion based bioprinting, DLP printing is generally faster due to its simultaneous layer curing process, and typically provides high resolution, resulting in smooth surface finishes with fine detail. Overall, DLP is a versatile and efficient 3D printing technology suitable for a wide range of applications, particularly those requiring high precision and detail.
More information and a step by step protocol can be found under the "More Documents" section of this page.
About the material:
The low endotoxin TissueFab® DLP bioink, synthetic, Vis/405nm contains:
*Low endotoxin, xeno-free, synthetic bioink precursor
*UV photoabsorber
Printing and crosslinking parameters:
*Suitable for DLP bioprinting
* Photoinitiator-assisted crosslinking at 405nm wavelength (Visible light)
The TissueFab® bioink DLP is a xeno-free, synthetic bionk used for DLP 3D bioprinting applications. This bioink is free of animal derived components, and offers batch-to-batch consistency with minimal risk of contamination (ie. bioburden or endotoxin). The TissueFab® bioink DLP is an effective bioink for fabricating cell-encapsulated scaffolds with sutiable microenvrionmental conditions for tissue engineering and regenerative medicine applications. This bioink photopolymerizes rapidly by mixing with the Ruthenium photoinitiator kit (916881) to create high resolution hydrogels with structural integrity. This xeno-free synthetic bioink is biocompatible, biodegradable, and promotes cellular function. Digital Light Processing (DLP) bioprinting is a 3D printing technology that uses projected light to selectively cure or harden photpolymer resins layer by layer to create three-dimensional (3D) objects. DLP is well known for its printing speed and precision. Compared to extrusion based bioprinting, DLP printing is generally faster due to its simultaneous layer curing process, and typically provides high resolution, resulting in smooth surface finishes with fine detail. Overall, DLP is a versatile and efficient 3D printing technology suitable for a wide range of applications, particularly those requiring high precision and detail.
More information and a step by step protocol can be found under the "More Documents" section of this page.
Application
The TissueFab® bionk DLP can be used in a variety of tissue engineering, regenerative medicine and in vitro modeling applications including:
* Musculoskeletal tissue engineering and regeneration including bone, cartilage, and skin
* Stem cell encapsulation and differentiation
* In vitro vascularized tissue modeling for drug discovery including lung and heart tissue
* Therapuetic delivery tools for large modalities including cell therapies
* High resolution printing to recapitulate microenvironments
* Musculoskeletal tissue engineering and regeneration including bone, cartilage, and skin
* Stem cell encapsulation and differentiation
* In vitro vascularized tissue modeling for drug discovery including lung and heart tissue
* Therapuetic delivery tools for large modalities including cell therapies
* High resolution printing to recapitulate microenvironments
Features and Benefits
Each TissueFab® bioink is developed and tested to meet strict criteria to best suit researchers′ needs. This includes:
High resolution printing: rapid polymerization compared to other 3D bioprinting technologies such as extrusion with optimized shape integrity and fidelity
Tunable mechanical properties: can be used in a variety of concentrations to better mimic native tissues
Cell viability and biocompatibility: A xeno-free biocompatible and biodegradable bioink that promotes cellular function
Low bioburden and low endotoxin
This product contains 500mg of bioink precursor. Dissolve in water, PBS, or cell culture media for a ready-to-use bioink.
High resolution printing: rapid polymerization compared to other 3D bioprinting technologies such as extrusion with optimized shape integrity and fidelity
Tunable mechanical properties: can be used in a variety of concentrations to better mimic native tissues
Cell viability and biocompatibility: A xeno-free biocompatible and biodegradable bioink that promotes cellular function
Low bioburden and low endotoxin
This product contains 500mg of bioink precursor. Dissolve in water, PBS, or cell culture media for a ready-to-use bioink.
Legal Information
TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Regulatory Information
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Mian Wang et al.
Advanced materials (Deerfield Beach, Fla.), 34(1), e2107038-e2107038 (2021-10-06)
Recapitulation of complex tissues signifies a remarkable challenge and, to date, only a few approaches have emerged that can efficiently reconstruct necessary gradients in 3D constructs. This is true even though mimicry of these gradients is of great importance to
Wei Zhu et al.
Biomaterials, 124, 106-115 (2017-02-14)
Living tissues rely heavily on vascular networks to transport nutrients, oxygen and metabolic waste. However, there still remains a need for a simple and efficient approach to engineer vascularized tissues. Here, we created prevascularized tissues with complex three-dimensional (3D) microarchitectures
Shangting You et al.
Science advances, 9(8), eade7923-eade7923 (2023-02-23)
Three-dimensional (3D) bioprinting techniques have emerged as the most popular methods to fabricate 3D-engineered tissues; however, there are challenges in simultaneously satisfying the requirements of high cell density (HCD), high cell viability, and fine fabrication resolution. In particular, bioprinting resolution
Qijiang Mao et al.
Materials science & engineering. C, Materials for biological applications, 109, 110625-110625 (2020-04-02)
As one of the most effective treatments of end-stage liver disease, liver transplantation still suffers from a shortage of donor organs or a low degree of engraftment. Thus, alternatives to liver transplantation, such as liver support systems, have to be
Claire Yu et al.
Biomaterials, 194, 1-13 (2018-12-19)
Decellularized extracellular matrices (dECMs) have demonstrated excellent utility as bioscaffolds in recapitulating the complex biochemical microenvironment, however, their use as bioinks in 3D bioprinting to generate functional biomimetic tissues has been limited by their printability and lack of tunable physical
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