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About This Item
Empirical Formula (Hill Notation):
C12H13NO4
CAS Number:
Molecular Weight:
235.24
MDL number:
Assay
>90% (HPLC)
Quality Level
solubility
chloroform: 15 mg (/0.5ml)
storage temp.
2-8°C
SMILES string
O=C1CCC(N1OC(C2C3C=CC(C3)C2)=O)=O
Related Categories
General description
5-Norbornene-2-carboxylate NHS Ester is a versatile and functional compound designed for a wide range of applications in bioconjugation and polymer chemistry. This compound features an N-Hydroxysuccinimide (NHS) ester, which allows for efficient reactions with amine-containing compounds, such as lysine residues on proteins and peptides. The norbornene structure facilitates bioorthogonal reactions, particularly the inverse electron demand Diels-Alder cycloaddition with 1,2,4,5-tetrazines, making it invaluable for biological imaging and advanced polymer synthesis.
Application
5-Norbornene-2-carboxylate NHS Ester is used in a wide range of applications including:
- Protein Labeling: Efficiently labels proteins and peptides through reactions with amines.
- Conjugate Preparation: Prepares conjugates for immunoassays and other analytical techniques.
- Fluorescent Labeling: Facilitates the labeling of enzymes for detection and analysis.
- Enzyme Immobilization: Works with EDC to immobilize enzymes for biosensor applications.
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