943479
7-(Diethylamino)-4-(hydroxymethyl)coumarin
≥95%
Synonym(s):
2H-1-Benzopyran-2-one, 7-(diethylamino)-4-(hydroxymethyl)-; 7-(Diethylamino)-4-(hydroxymethyl)-2H-1-benzopyran-2-one; 7-(Diethylamino)-4-(hydroxymethyl)-2H-chromen-2-one; 7-(Diethylamino)-4-(hydroxymethyl)-2H-chromene-2-one
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About This Item
Empirical Formula (Hill Notation):
C14H17NO3
CAS Number:
Molecular Weight:
247.29
MDL number:
Assay:
≥95%
Form:
amorphous solid
Quality Level
assay
≥95%
form
amorphous solid
color
off-white to gray-brown
functional group
(hydroxymethyl substitution at the 4-position and a diethylamino group at the 7-position)
storage temp.
2-8°C
SMILES string
O=C1OC=2C=C(C=CC2C(=C1)CO)N(CC)CC
InChI
InChI=1S/C14H17NO3/c1-3-15(4-2)11-5-6-12-10(9-16)7-14(17)18-13(12)8-11/h5-8,16H,3-4,9H2,1-2H3
InChI key
NMZSXNOCNJMJQT-UHFFFAOYSA-N
General description
7-(Diethylamino)-4-(hydroxymethyl)coumarin, commonly abbreviated DEACM, is a coumarin-based fluorescent compound widely used as a photoremovable protecting group (PPG) and fluorescent probe. It belongs to the class of coumarin derivatives, featuring a hydroxymethyl substitution at the 4-position and a diethylamino group at the 7-position, giving it strong photophysical properties.
Application
A coumarin derivative useful for generation of photocontrolled PROTACs(photoPROTACs) that can cause on demand degradation using 365nm light.
Features and Benefits
DEACM absorbs light in the near-UV to blue region (~365 nm) and exhibits bright fluorescence, making it especially valuable for photo-controlled release applications (“caging” techniques), biological imaging, and fluorescent sensing. Because of its excellent quantum yield and chemical stability, DEACM is widely adopted in fields such as chemical biology, pharmaceutical R&D, photochemistry, and analytical sciences.
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 943479-50MG | 04065273614572 |