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Merck
CN

945749

Thiol Functionalized Poly(2-ethyl-2-oxazoline)

Mn 5 kDa

Synonym(s):

POx-SH, Poly(2-ethyl-2-oxazoline), Poly(2-ethyl-2-oxazoline) thiol

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SMILES string

[*]N(C(CC)=O)CCOC(CCS)=O

form

powder

mol wt

Mn 5 kDa

color

white to pale yellow

application(s)

3D bioprinting
tissue engineering
(Hydrogels)

storage temp.

−20°C

Quality Level

General description

Thiol-functionalized poly(2-ethyl-2-oxazoline) (PEOz) is a versatile synthetic polymer characterized by the incorporation of thiol (-SH) groups into its structure. This modification significantly enhances its reactivity and expands its potential applications in fields such as biomedicine, materials science, and nanotechnology.

Application

Thiol Functionalizeed Poly(2-ethyl-2-oxazoline), Mn 5KDa can be used in research areas of drug delivery systems, where the thiol groups facilitate the attachment of drugs and targeting moieties, enhancing the specificity and efficiency.


Studies have explored how varying the degree of dodecyl functionalization affects the thermal, self-assembly, and drug encapsulation behaviors of these polymers, demonstrating their potential for smart material applications.


Thiol-functionalized poly(2-ethyl-2-oxazoline) represents a promising platform for developing advanced materials with tailored functionalities, particularly in the biomedical and materials science sectors.

Features and Benefits

  1. Thiol-functionalized PEOz exhibits good solubility in water and organic solvents, making it adaptable for various formulations. Its stability in physiological conditions is beneficial for drug delivery applications.
  2. The ability to form cross-linked networks via thiol-disulfide exchanges can be exploited to develop hydrogels and scaffolds for tissue engineering.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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