94814
3-(3-Pyridyl)-L-alanine
≥98.0% (HPLC)
Synonym(s):
(S)-2-Amino-3-(3-pyridyl)propionic acid, 3′-Aza-L-phenylalanine
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About This Item
Empirical Formula (Hill Notation):
C8H10N2O2
CAS Number:
Molecular Weight:
166.18
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4351583
Product Name
3-(3-Pyridyl)-L-alanine, ≥98.0% (HPLC)
InChI
1S/C8H10N2O2/c9-7(8(11)12)4-6-2-1-3-10-5-6/h1-3,5,7H,4,9H2,(H,11,12)/t7-/m0/s1
SMILES string
N[C@@H](Cc1cccnc1)C(O)=O
InChI key
DFZVZEMNPGABKO-ZETCQYMHSA-N
assay
≥98.0% (HPLC)
form
powder
reaction suitability
reaction type: solution phase peptide synthesis
application(s)
peptide synthesis
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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P N Rao et al.
International journal of peptide and protein research, 29(1), 118-125 (1987-01-01)
The DL-arylamino acid ethyl ester derivatives of beta-(3-pyridyl)-DL-alanine, and beta-(3-benzo[b]thienyl)-DL-alanine were synthesized by diethyl acetamidomalonate condensation with the respective arylmethyl halides followed by partial hydrolysis to the monoethyl ester and decarboxylation. Each derivative was enzymatically resolved to a separable mixture
H Shimeno et al.
Journal of enzyme inhibition, 2(1), 57-66 (1987-01-01)
Single doses of DL-alpha-amino-beta-(2-pyridine)propanoic acid (2-PA, 100 mg/kg) significantly decreased the holoenzyme and apoenzyme activities of rat liver tryptophan pyrrolase (TP) and increased brain tryptophan, serotonin (5-HT) and 5-hydroxyindole-3-ylacetic acid concentrations. 2-PA had no inhibitory effect on either of the
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