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C65408

2-(4-Chlorophenyl)ethylamine

Name: 2-(4-Chlorophenyl)ethylamine
Brand: ALDRICH

98%

Synonym(s):

4-Chlorophenethylamine

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About This Item

Linear Formula:

ClC₆H₄CH₂CH₂NH₂

CAS Number:

156-41-2

Molecular Weight:

155.62

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24892877

EC Number:

205-853-4

Beilstein/REAXYS Number:

508247

MDL number:

MFCD00008191

Assay:

98%

Form:

liquid

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Quality Level

100

assay

98%

form

liquid

drug control

Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet

refractive index

n20/D 1.548 (lit.)

bp

60-65 °C/0.1 mmHg (lit.)

density

1.112 g/mL at 25 °C (lit.)

SMILES string

NCCc1ccc(Cl)cc1

InChI

1S/C8H10ClN/c9-8-3-1-7(2-4-8)5-6-10/h1-4H,5-6,10H2

InChI key

SRXFXCKTIGELTI-UHFFFAOYSA-N

Related Categories

Organic Building Blocks

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

222.8 °F - closed cup

flash_point_c

106 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Para-chlorophenylethylamine in brains of rats treated with a monoamine oxidase inhibitor and p-chlorophenylalanine.

G B Baker et al.

Progress in neuro-psychopharmacology & biological psychiatry, 6(4-6), 343-346 (1982-01-01)

1. The accumulation of p-chlorophenylethylamine (pCPE) in rat brain after administration of pargyline plus p-chlorophenylalanine (pCPA) is demonstrated. 2. Measurements of pCPE in brain were performed at 0.25 h, 1 h and 4 h after administration of pCPA to pargyline-pretreated

Harmane inhibits serotonergic dorsal raphe neurons in the rat.

Khalid Touiki et al.

Psychopharmacology, 182(4), 562-569 (2005-09-01)

Harmane and norharmane (two beta-carbolines) are tobacco components or products. The effects of harmane and norharmane on serotonergic raphe neurons remain unknown. Harmane and norharmane are inhibitors of the monoamine oxidases A (MAO-A) and B (MAO-B), respectively. To study the

The role of serotonin release and autoreceptors in the dorsalis raphe nucleus in the control of serotonin release in the cat caudate nucleus.

D Becquet et al.

Neuroscience, 39(3), 639-647 (1990-01-01)

Using a push-pull cannula technique and an isotopic method for estimating [3H]serotonin continuously synthesized from [3H]tryptophan, the effects of changes in the release of serotonin in the dorsalis raphe nucleus on in vivo release of [3H]serotonin in the cat caudate

The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism.

Giulia Guiducci et al.

Nucleic acids research, 47(8), 4240-4254 (2019-02-28)

Enzymes of intermediary metabolism are often reported to have moonlighting functions as RNA-binding proteins and have regulatory roles beyond their primary activities. Human serine hydroxymethyltransferase (SHMT) is essential for the one-carbon metabolism, which sustains growth and proliferation in normal and

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.

Marina Marani et al.

Oncotarget, 7(4), 4570-4583 (2015-12-31)

Serine hydroxymethyltransferase (SHMT) is a central enzyme in the metabolic reprogramming of cancer cells, providing activated one-carbon units in the serine-glycine one-carbon metabolism. Previous studies demonstrated that the cytoplasmic isoform of SHMT (SHMT1) plays a relevant role in lung cancer.

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Global Trade Item Number

SKU	GTIN
C65408-5G	04061832105017
C65408-25G	04061833511343

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