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Merck
CN

C65408

2-(4-Chlorophenyl)ethylamine

98%

Synonym(s):

4-Chlorophenethylamine

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About This Item

Linear Formula:
ClC6H4CH2CH2NH2
CAS Number:
Molecular Weight:
155.62
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-853-4
Beilstein/REAXYS Number:
508247
MDL number:
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Product Name

2-(4-Chlorophenyl)ethylamine, 98%

InChI

1S/C8H10ClN/c9-8-3-1-7(2-4-8)5-6-10/h1-4H,5-6,10H2

InChI key

SRXFXCKTIGELTI-UHFFFAOYSA-N

SMILES string

NCCc1ccc(Cl)cc1

assay

98%

form

liquid

Quality Level

drug control

Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet

refractive index

n20/D 1.548 (lit.)

bp

60-65 °C/0.1 mmHg (lit.)

density

1.112 g/mL at 25 °C (lit.)

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Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

222.8 °F - closed cup

flash_point_c

106 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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T N Mellin et al.
The American journal of tropical medicine and hygiene, 32(1), 83-93 (1983-01-01)
Neuropharmacological studies of Schistosoma mansoni were conducted in vitro using visual observations of motor activity and measurements of worm length and extracellular electrical activity. The instrumentation and methodology described quantitatively measure extracellular electrical potentials associated with motor activity, and provide
E Chung Hwang et al.
The Journal of pharmacology and experimental therapeutics, 213(2), 254-260 (1980-05-01)
A series of substituted phenylethylamines were examined for their relative potencies to 1) release and inhibit accumulation of labeled serotonin in brain synaptosomes, 2) compete with serotonin receptor binding and 3) induce the "serotonin syndrome" in mice. In general, the
Giulia Guiducci et al.
Nucleic acids research, 47(8), 4240-4254 (2019-02-28)
Enzymes of intermediary metabolism are often reported to have moonlighting functions as RNA-binding proteins and have regulatory roles beyond their primary activities. Human serine hydroxymethyltransferase (SHMT) is essential for the one-carbon metabolism, which sustains growth and proliferation in normal and
G B Baker et al.
Progress in neuro-psychopharmacology & biological psychiatry, 6(4-6), 343-346 (1982-01-01)
1. The accumulation of p-chlorophenylethylamine (pCPE) in rat brain after administration of pargyline plus p-chlorophenylalanine (pCPA) is demonstrated. 2. Measurements of pCPE in brain were performed at 0.25 h, 1 h and 4 h after administration of pCPA to pargyline-pretreated
Marina Marani et al.
Oncotarget, 7(4), 4570-4583 (2015-12-31)
Serine hydroxymethyltransferase (SHMT) is a central enzyme in the metabolic reprogramming of cancer cells, providing activated one-carbon units in the serine-glycine one-carbon metabolism. Previous studies demonstrated that the cytoplasmic isoform of SHMT (SHMT1) plays a relevant role in lung cancer.

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